ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: perforin 1 (pore forming protein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000180644 PRF1 9606 - 10:70597348-70602775 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373209 PRF1-001 70597348-70602759 protein_coding
  ENST00000441259 PRF1-201 70597349-70602775 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000373209
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000373209 0.014±0.00 0.017±0.01 0.102±0.00 0.035±0.03

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002357 ISS defense response to tumor cell
GO:0002418 ISS immune response to tumor cell
GO:0005509 ISS calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0005768 IEA endosome
GO:0005886 IEA plasma membrane
GO:0006915 TAS apoptotic process
GO:0006968 TAS cellular defense response
GO:0016020 IDA membrane
GO:0016021 IDA integral component of membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0019835 ISS cytolysis
GO:0022829 IDA wide pore channel activity
GO:0044194 ISS cytolytic granule
GO:0051260 IDA protein homooligomerization
GO:0051607 ISS defense response to virus
GO:0055085 IDA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001572 prf1.3 protein_coding Danio_rerio
ENSDARG00000021444 prf1.2 protein_coding Danio_rerio
ENSDARG00000024522 prf1.6 protein_coding Danio_rerio
ENSDARG00000030394 prf1.1 protein_coding Danio_rerio
ENSDARG00000037598 prf1.5 protein_coding Danio_rerio
ENSDARG00000060662 prf1.9 protein_coding Danio_rerio
ENSDARG00000073969 prf1.7 protein_coding Danio_rerio
ENSDARG00000089259 prf1.8 protein_coding Danio_rerio
ENSMUSG00000037202 Prf1 protein_coding Mus_musculus

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