| Transcript ID | BECs | HAoEC | HHSEC | HUVEC |
|---|---|---|---|---|
| ENST00000373209 | 0.014±0.00 | 0.017±0.01 | 0.102±0.00 | 0.035±0.03 |
Gene Info | |||||
|---|---|---|---|---|---|
| Description: | perforin 1 (pore forming protein) | ||||
| Gene Accession | Gene Name | Tax ID | Strand | Position | Gene Biotype |
|
ENSG00000180644 |
PRF1 | 9606 | - |
10:70597348-70602775 |
protein_coding |
| Transcript Accession | Transcript Name | Position | Transcript Biotype | ||
| ENST00000373209 |
PRF1-001 | 70597348-70602759 | protein_coding | ||
| ENST00000441259 |
PRF1-201 | 70597349-70602775 | protein_coding | ||
Expression Patterns
|
Conserved Regions |
|---|
| Not located within a conserved region. |
Gene Ontology |
||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0002357 | ISS | defense response to tumor cell |
| GO:0002418 | ISS | immune response to tumor cell |
| GO:0005509 | ISS | calcium ion binding |
| GO:0005515 | IPI:IEA | protein binding |
| GO:0005576 | IEA | extracellular region |
| GO:0005768 | IEA | endosome |
| GO:0005886 | IEA | plasma membrane |
| GO:0006915 | TAS | apoptotic process |
| GO:0006968 | TAS | cellular defense response |
| GO:0016020 | IDA | membrane |
| GO:0016021 | IDA | integral component of membrane |
| GO:0016023 | IEA | cytoplasmic membrane-bounded vesicle |
| GO:0019835 | ISS | cytolysis |
| GO:0022829 | IDA | wide pore channel activity |
| GO:0044194 | ISS | cytolytic granule |
| GO:0051260 | IDA | protein homooligomerization |
| GO:0051607 | ISS | defense response to virus |
| GO:0055085 | IDA | transmembrane transport |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Description | Biotype | Species | |
|
ENSDARG00000001572
|
prf1.3 | protein_coding | Danio_rerio | ||
|
ENSDARG00000021444
|
prf1.2 | protein_coding | Danio_rerio | ||
|
ENSDARG00000024522
|
prf1.6 | protein_coding | Danio_rerio | ||
|
ENSDARG00000030394
|
prf1.1 | protein_coding | Danio_rerio | ||
|
ENSDARG00000037598
|
prf1.5 | protein_coding | Danio_rerio | ||
|
ENSDARG00000060662
|
prf1.9 | protein_coding | Danio_rerio | ||
|
ENSDARG00000073969
|
prf1.7 | protein_coding | Danio_rerio | ||
|
ENSDARG00000089259
|
prf1.8 | protein_coding | Danio_rerio | ||
|
ENSMUSG00000037202
|
Prf1 | protein_coding | Mus_musculus | ||