ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ring finger protein 41, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181852 RNF41 9606 - 12:56202175-56221933 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000345093 RNF41-001 56202175-56221921 protein_coding
  ENST00000394013 RNF41-002 56205450-56221909 protein_coding
  ENST00000547967 RNF41-005 56205450-56221866 nonsense_mediated_decay
  ENST00000548120 RNF41-008 56206587-56208544 retained_intron
  ENST00000548225 RNF41-003 56210037-56221860 retained_intron
  ENST00000549038 RNF41-011 56207677-56221701 protein_coding
  ENST00000549119 RNF41-009 56208148-56216606 nonsense_mediated_decay
  ENST00000550379 RNF41-007 56210248-56214018 retained_intron
  ENST00000551711 RNF41-013 56206749-56221922 protein_coding
  ENST00000552244 RNF41-010 56207639-56221843 protein_coding
  ENST00000552656 RNF41-006 56206447-56221933 protein_coding
  ENST00000615206 RNF41-201 56202504-56221701 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000345093ENST00000394013ENST00000548225ENST00000551711ENST00000552244ENST00000552656ENST00000615206
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000345093 N/A 4.282±0.88 3.737±0.00 6.842±5.34
ENST00000394013 2.824±0.00 14.341±3.86 5.438±0.00 12.864±10.00
ENST00000548225 2.564±0.00 N/A N/A N/A
ENST00000551711 N/A N/A N/A 1.006±0.00
ENST00000552244 N/A N/A N/A 21.562±0.00
ENST00000552656 N/A 13.212±4.42 7.431±0.00 23.200±19.25
ENST00000615206 N/A 4.422±1.42 N/A 2.217±1.22

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0004842 IEA:IDA ubiquitin-protein transferase activity
GO:0005128 IEA erythropoietin receptor binding
GO:0005135 IEA interleukin-3 receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0008270 IEA zinc ion binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0010468 IEA regulation of gene expression
GO:0010498 IDA proteasomal protein catabolic process
GO:0016567 IEA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0030336 IMP negative regulation of cell migration
GO:0031386 IEA protein tag
GO:0043408 IDA regulation of MAPK cascade
GO:0045619 IEA regulation of lymphocyte differentiation
GO:0045637 IEA regulation of myeloid cell differentiation
GO:0046872 IEA metal ion binding
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051865 IDA protein autoubiquitination
GO:0051896 IDA regulation of protein kinase B signaling
GO:0097191 IDA extrinsic apoptotic signaling pathway
GO:2000114 IEA regulation of establishment of cell polarity
GO:2000377 IMP regulation of reactive oxygen species metabolic process
GO:2000379 IMP positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036831 rnf41 protein_coding Danio_rerio
ENSMUSG00000025373 Rnf41 protein_coding Mus_musculus

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