ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: izumo sperm-egg fusion 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182264 IZUMO1 9606 - 19:48740852-48746909 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332955 IZUMO1-001 48740888-48746909 protein_coding
  ENST00000595517 IZUMO1-004 48740908-48745859 nonsense_mediated_decay
  ENST00000595937 IZUMO1-003 48740908-48745859 nonsense_mediated_decay
  ENST00000597553 IZUMO1-002 48743032-48746180 retained_intron
  ENST00000599871 IZUMO1-005 48740852-48741523 retained_intron
  ENST00000602105 IZUMO1-006 48744464-48746797 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000332955ENST00000595517ENST00000595937ENST00000597553ENST00000599871ENST00000602105
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000332955 N/A 0.086±0.00 N/A N/A 0.039±0.02
ENST00000595517 N/A 0.090±0.03 3.262±0.00 0.092±0.00 0.053±0.00
ENST00000595937 N/A N/A 2.603±0.00 N/A 0.059±0.00
ENST00000597553 0.201±0.00 0.133±0.08 1.093±0.00 0.103±0.00 0.077±0.06
ENST00000599871 2.139±1.79 0.491±0.17 12.577±0.00 0.505±0.00 0.333±0.18
ENST00000602105 N/A N/A N/A N/A 0.824±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001669 IEA acrosomal vesicle
GO:0002080 IEA acrosomal membrane
GO:0005102 IPI receptor binding
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0007155 IC cell adhesion
GO:0007338 ISS single fertilization
GO:0007342 IDA fusion of sperm to egg plasma membrane
GO:0016021 IDA integral component of membrane
GO:0032504 TAS multicellular organism reproduction
GO:0035036 ISS sperm-egg recognition
GO:0042803 ISS protein homodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000064158 Izumo1 protein_coding Mus_musculus

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