ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182481 KPNA2 9606 + 17:68035519-68046842 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330459 KPNA2-001 68035519-68046842 protein_coding
  ENST00000537025 KPNA2-002 68035960-68046842 protein_coding
  ENST00000579754 KPNA2-003 68036994-68042212 protein_coding
  ENST00000582898 KPNA2-007 68045468-68046629 processed_transcript
  ENST00000583269 KPNA2-005 68035708-68042209 nonsense_mediated_decay
  ENST00000583392 KPNA2-006 68042912-68043892 retained_intron
  ENST00000584026 KPNA2-004 68035735-68042184 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000330459ENST00000537025ENST00000582898ENST00000584026
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000330459 9.365±0.00 69.229±22.86 4.170±0.00 63.543±0.00 61.263±31.95
ENST00000537025 N/A N/A N/A N/A 2.133±0.00
ENST00000582898 124.678±39.19 N/A 12.328±0.00 N/A N/A
ENST00000584026 N/A 70.055±15.36 N/A N/A 89.870±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000018 TAS regulation of DNA recombination
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006259 TAS DNA metabolic process
GO:0006606 IEA protein import into nucleus
GO:0006607 IDA NLS-bearing protein import into nucleus
GO:0008139 IDA nuclear localization sequence binding
GO:0008565 IEA protein transporter activity
GO:0016020 IDA membrane
GO:0016032 IEA viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0042826 IPI histone deacetylase binding
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038066 kpna2 protein_coding Danio_rerio
ENSMUSG00000018362 Kpna2 protein_coding Mus_musculus
ENSMUSG00000066878 Gm10184 protein_coding Mus_musculus

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