ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: adaptor-related protein complex 2, alpha 2 subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183020 AP2A2 9606 + 11:924894-1012245 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332231 AP2A2-201 925809-1012245 protein_coding
  ENST00000448903 AP2A2-001 925881-1012239 protein_coding
  ENST00000524559 AP2A2-019 946461-977120 protein_coding
  ENST00000524952 AP2A2-014 985538-988827 retained_intron
  ENST00000525796 AP2A2-023 925872-985477 protein_coding
  ENST00000525891 AP2A2-012 996064-1009216 processed_transcript
  ENST00000526376 AP2A2-010 1003732-1007040 retained_intron
  ENST00000526401 AP2A2-025 1003667-1009774 retained_intron
  ENST00000526753 AP2A2-016 942279-972197 protein_coding
  ENST00000527024 AP2A2-020 940735-972216 protein_coding
  ENST00000527917 AP2A2-015 985384-986846 retained_intron
  ENST00000528195 AP2A2-013 925945-1000483 processed_transcript
  ENST00000528815 AP2A2-002 925900-1010919 nonsense_mediated_decay
  ENST00000528816 AP2A2-009 1009355-1010237 retained_intron
  ENST00000529427 AP2A2-011 1006544-1008282 retained_intron
  ENST00000529438 AP2A2-024 1001326-1009366 processed_transcript
  ENST00000529818 AP2A2-021 924894-977193 processed_transcript
  ENST00000529858 AP2A2-008 925870-970233 processed_transcript
  ENST00000530801 AP2A2-022 943100-972191 protein_coding
  ENST00000531497 AP2A2-005 1006709-1010926 retained_intron
  ENST00000531548 AP2A2-017 932693-977157 protein_coding
  ENST00000534328 AP2A2-004 925880-1010919 protein_coding
  ENST00000534485 AP2A2-018 933561-977207 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000332231ENST00000448903ENST00000528815ENST00000531497ENST00000534328
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000332231 N/A 3.138±0.00 N/A N/A 4.669±1.79
ENST00000448903 N/A 1.908±0.00 N/A N/A 9.270±5.98
ENST00000528815 11.588±0.34 20.798±7.02 13.986±0.00 15.683±0.00 16.596±9.73
ENST00000531497 N/A N/A 8.051±0.00 N/A 6.812±3.76
ENST00000534328 N/A N/A N/A N/A 6.876±0.12

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003EW CIL_0003EW_0001 CGP
CIL_0003EX CIL_0003EX_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006886 IEA intracellular protein transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008289 IEA lipid binding
GO:0008565 IEA protein transporter activity
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0016032 TAS viral process
GO:0016192 IEA vesicle-mediated transport
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 ISS protein kinase binding
GO:0030117 IEA membrane coat
GO:0030131 IEA clathrin adaptor complex
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050690 TAS regulation of defense response to virus by virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000002957 Ap2a2 protein_coding Mus_musculus

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