ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Mix paired-like homeobox
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185155 MIXL1 9606 + 1:226223618-226227054 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366810 MIXL1-001 226223618-226227054 protein_coding
  ENST00000542034 MIXL1-002 226223618-226225864 protein_coding
  ENST00000557734 MIXL1-003 226225503-226226389 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000366810ENST00000542034ENST00000557734
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000366810 0.126±0.00 0.177±0.11 0.228±0.00 0.122±0.00 0.169±0.13
ENST00000542034 N/A 0.260±0.09 N/A N/A 0.109±0.00
ENST00000557734 N/A 0.366±0.26 N/A 0.120±0.00 0.263±0.17

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000BW CIL_0000BW_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 ISS nuclear chromatin
GO:0000978 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 ISS RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000987 ISS core promoter proximal region sequence-specific DNA binding
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001085 ISS RNA polymerase II transcription factor binding
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0001190 ISS RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001205 ISS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001706 IEA endoderm formation
GO:0002244 ISS hematopoietic progenitor cell differentiation
GO:0003677 IEA DNA binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007369 ISS gastrulation
GO:0007492 ISS endoderm development
GO:0007507 ISS heart development
GO:0030097 IEA hemopoiesis
GO:0035987 ISS endodermal cell differentiation
GO:0042074 IEA cell migration involved in gastrulation
GO:0042803 ISS protein homodimerization activity
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048565 ISS digestive tract development
GO:1901533 ISS negative regulation of hematopoietic progenitor cell differentiation
GO:2000382 ISS positive regulation of mesoderm development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015906 mxtx2 protein_coding Danio_rerio
ENSDARG00000069252 mixl1 protein_coding Danio_rerio
ENSDARG00000069382 mxtx1 protein_coding Danio_rerio
ENSMUSG00000026497 Mixl1 protein_coding Mus_musculus

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