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ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: neuregulin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185737 NRG3 9606 + 10:81875314-82987179 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000372141 NRG3-004 81875314-82985645 protein_coding
  ENST00000372142 NRG3-001 81877687-82986967 protein_coding
  ENST00000404547 NRG3-005 81875341-82985605 protein_coding
  ENST00000404576 NRG3-003 81877961-82985605 protein_coding
  ENST00000537893 NRG3-201 82799742-82985605 protein_coding
  ENST00000545131 NRG3-202 82738576-82987179 protein_coding
  ENST00000555784 NRG3-006 81877961-82985605 nonsense_mediated_decay
  ENST00000556918 NRG3-002 81877961-82985605 protein_coding
  ENST00000602794 NRG3-007 81877897-82987179 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000372141ENST00000372142ENST00000404547ENST00000545131ENST00000555784ENST00000602794
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000372141 0.086±0.07 0.066±0.06 N/A N/A 0.439±0.21
ENST00000372142 N/A N/A N/A 0.525±0.00 N/A
ENST00000404547 0.020±0.00 0.094±0.07 N/A N/A 0.479±0.32
ENST00000545131 N/A 0.044±0.01 3.497±0.00 N/A 0.244±0.11
ENST00000555784 N/A 0.074±0.02 N/A N/A N/A
ENST00000602794 0.052±0.00 0.057±0.02 N/A 1.264±0.00 0.107±0.02

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005NZ CIL_0005NZ_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001558 NAS regulation of cell growth
GO:0005102 IEA receptor binding
GO:0005515 IEA protein binding
GO:0005576 NAS extracellular region
GO:0005887 NAS integral component of plasma membrane
GO:0007171 NAS activation of transmembrane receptor protein tyrosine kinase activity
GO:0007389 IEA pattern specification process
GO:0008083 NAS growth factor activity
GO:0009790 IEA embryo development
GO:0030297 NAS transmembrane receptor protein tyrosine kinase activator activity
GO:0030879 IEA mammary gland development
GO:0030971 NAS receptor tyrosine kinase binding
GO:0035556 IEA intracellular signal transduction
GO:0060596 IEA mammary placode formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089766 nrg3b protein_coding Danio_rerio
ENSMUSG00000041014 Nrg3 protein_coding Mus_musculus

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