ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: nonhomologous end-joining factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000187736 NHEJ1 9606 - 2:219075317-219160865 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356853 NHEJ1-001 219075321-219160853 protein_coding
  ENST00000409720 NHEJ1-004 219075317-219158362 protein_coding
  ENST00000418099 NHEJ1-006 219075329-219160798 nonsense_mediated_decay
  ENST00000426304 NHEJ1-009 219076303-219157621 protein_coding
  ENST00000450447 NHEJ1-005 219146707-219160865 nonsense_mediated_decay
  ENST00000457600 NHEJ1-008 219078107-219160555 protein_coding
  ENST00000481764 NHEJ1-007 219158820-219160762 processed_transcript
  ENST00000483627 NHEJ1-010 219076378-219125660 processed_transcript
  ENST00000491159 NHEJ1-002 219076318-219125652 processed_transcript
  ENST00000494211 NHEJ1-003 219076292-219124764 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000356853ENST00000409720ENST00000450447ENST00000457600
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000356853 2.233±0.00 3.480±1.65 3.940±0.00 5.009±2.49
ENST00000409720 1.482±0.00 3.535±1.30 N/A 1.924±0.32
ENST00000450447 N/A 3.070±0.00 N/A 6.682±1.24
ENST00000457600 N/A 2.547±0.00 N/A 4.063±3.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001HY CIL_0001HY_0002 CGP
CIL_0006EF CIL_0006EF_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0006281 IEA DNA repair
GO:0006302 IEA double-strand break repair
GO:0006303 IMP double-strand break repair via nonhomologous end joining
GO:0006310 IEA DNA recombination
GO:0007417 NAS central nervous system development
GO:0010212 IDA response to ionizing radiation
GO:0030183 IMP B cell differentiation
GO:0030217 IMP T cell differentiation
GO:0051351 NAS positive regulation of ligase activity
GO:0070419 IDA nonhomologous end joining complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058893 nhej1 protein_coding Danio_rerio
ENSMUSG00000026162 Nhej1 protein_coding Mus_musculus

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