ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: indoleamine 2,3-dioxygenase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188676 IDO2 9606 + 8:39934614-40016391 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343295 IDO2-001 39934614-40016391 processed_transcript
  ENST00000389060 IDO2-004 39949166-40015605 protein_coding
  ENST00000418094 IDO2-003 39987743-40016391 processed_transcript
  ENST00000502986 IDO2-201 39934955-40016391 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000343295ENST00000418094
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000343295 0.059±0.00 0.025±0.02 0.061±0.00 0.031±0.00 0.036±0.05
ENST00000418094 N/A N/A N/A N/A 0.014±0.01

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004833 EXP tryptophan 2,3-dioxygenase activity
GO:0005737 ISS cytoplasm
GO:0005829 TAS cytosol
GO:0006569 TAS tryptophan catabolic process
GO:0019441 IEA tryptophan catabolic process to kynurenine
GO:0020037 IEA heme binding
GO:0033754 ISS indoleamine 2,3-dioxygenase activity
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033594 ido1 protein_coding Danio_rerio
ENSMUSG00000031549 Ido2 protein_coding Mus_musculus

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