ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: claudin 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000189143 CLDN4 9606 + 7:73799542-73832693 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340958 CLDN4-201 73830863-73832693 protein_coding
  ENST00000431918 CLDN4-001 73828174-73832683 protein_coding
  ENST00000435050 CLDN4-002 73827744-73832684 protein_coding
  ENST00000466411 CLDN4-003 73799542-73829366 processed_transcript
  ENST00000476494 CLDN4-004 73827745-73828950 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000340958ENST00000431918ENST00000435050ENST00000476494
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000340958 0.048±0.00 0.487±0.43 0.569±0.00 0.351±0.00 0.118±0.08
ENST00000431918 0.091±0.03 0.138±0.08 N/A 0.177±0.00 0.044±0.03
ENST00000435050 N/A 0.036±0.00 0.090±0.00 N/A 0.033±0.01
ENST00000476494 N/A N/A N/A N/A 0.192±0.14

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004888 TAS transmembrane signaling receptor activity
GO:0005198 IEA structural molecule activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IMP integral component of plasma membrane
GO:0005923 ISS tight junction
GO:0007165 TAS signal transduction
GO:0007565 IEA female pregnancy
GO:0009925 IEA basal plasma membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0016327 IEA apicolateral plasma membrane
GO:0016328 IEA lateral plasma membrane
GO:0016338 ISS calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0032570 IEA response to progesterone
GO:0042802 ISS identical protein binding
GO:0061436 IMP establishment of skin barrier

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015955 cldnc protein_coding Danio_rerio
ENSDARG00000069503 cldnh protein_coding Danio_rerio
ENSMUSG00000047501 Cldn4 protein_coding Mus_musculus

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