ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196155 PLEKHG4 9606 + 16:67277510-67289499 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360461 PLEKHG4-002 67277510-67289479 protein_coding
  ENST00000379344 PLEKHG4-005 67279524-67289473 protein_coding
  ENST00000393966 PLEKHG4-007 67279896-67289055 nonsense_mediated_decay
  ENST00000427155 PLEKHG4-004 67279238-67289479 protein_coding
  ENST00000450733 PLEKHG4-006 67279589-67289499 protein_coding
  ENST00000562144 PLEKHG4-011 67277820-67280273 protein_coding
  ENST00000562289 PLEKHG4-014 67287572-67289307 retained_intron
  ENST00000562744 PLEKHG4-017 67279147-67280934 protein_coding
  ENST00000563969 PLEKHG4-001 67277510-67289479 nonsense_mediated_decay
  ENST00000565773 PLEKHG4-013 67278834-67280368 protein_coding
  ENST00000565899 PLEKHG4-012 67278157-67280265 protein_coding
  ENST00000567136 PLEKHG4-020 67287950-67289072 nonsense_mediated_decay
  ENST00000567938 PLEKHG4-018 67279596-67280275 protein_coding
  ENST00000568621 PLEKHG4-019 67279553-67280152 protein_coding
  ENST00000569875 PLEKHG4-016 67287900-67288942 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000360461ENST00000379344ENST00000393966ENST00000427155ENST00000450733ENST00000562289ENST00000563969ENST00000565899ENST00000567136
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000360461 N/A N/A N/A N/A 0.304±0.00
ENST00000379344 N/A 3.999±1.04 N/A N/A 1.491±1.06
ENST00000393966 N/A 2.524±0.00 N/A N/A N/A
ENST00000427155 2.968±1.70 5.303±2.59 N/A 8.319±0.00 5.473±4.52
ENST00000450733 N/A 1.950±0.92 0.249±0.00 N/A 2.011±1.81
ENST00000562289 12.267±0.00 N/A N/A N/A N/A
ENST00000563969 N/A 0.621±0.16 N/A N/A 1.377±1.54
ENST00000565899 N/A N/A N/A N/A 7.874±0.29
ENST00000567136 13.248±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005JZ CIL_0005JZ_0002 CGP
CIL_00033E CIL_00033E_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000014782 Plekhg4 protein_coding Mus_musculus

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