ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: peptidylprolyl isomerase A (cyclophilin A)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196262 PPIA 9606 + 7:44796680-44824564 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355968 PPIA-002 44796681-44801631 protein_coding
  ENST00000415933 PPIA-007 44796682-44801624 nonsense_mediated_decay
  ENST00000451562 PPIA-006 44796680-44800011 protein_coding
  ENST00000468812 PPIA-001 44796680-44803117 protein_coding
  ENST00000479021 PPIA-009 44796681-44824564 nonsense_mediated_decay
  ENST00000480603 PPIA-008 44798814-44801624 processed_transcript
  ENST00000481437 PPIA-005 44796680-44799816 retained_intron
  ENST00000489459 PPIA-003 44796681-44801630 protein_coding
  ENST00000494484 PPIA-004 44797973-44801647 retained_intron
  ENST00000620047 PPIA-201 44796681-44801631 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000355968ENST00000415933ENST00000451562ENST00000468812ENST00000494484ENST00000620047
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000355968 1674.840±55.55 416.778±139.28 441.501±0.00 629.385±0.00 561.511±415.74
ENST00000415933 500.877±174.14 328.907±58.38 83.688±0.00 N/A 179.603±38.21
ENST00000451562 N/A 426.285±15.80 N/A 416.969±0.00 1066.043±552.40
ENST00000468812 N/A 52.706±15.27 23.751±0.00 46.143±0.00 69.572±32.10
ENST00000494484 N/A N/A N/A N/A 33.550±2.40
ENST00000620047 N/A N/A N/A N/A 127.394±43.74

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000SC CIL_0000SC_0001 CGP
CIL_0000SB CIL_0000SB_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000413 IDA:IEA protein peptidyl-prolyl isomerization
GO:0002576 TAS platelet degranulation
GO:0003755 IDA:IEA peptidyl-prolyl cis-trans isomerase activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005829 IDA cytosol
GO:0005925 IDA focal adhesion
GO:0006278 TAS RNA-dependent DNA replication
GO:0006457 TAS:IEA protein folding
GO:0007596 TAS blood coagulation
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0019058 TAS viral life cycle
GO:0019061 TAS uncoating of virus
GO:0019068 TAS virion assembly
GO:0019076 TAS viral release from host cell
GO:0030168 TAS platelet activation
GO:0030260 TAS entry into host cell
GO:0034389 IMP lipid particle organization
GO:0042277 IEA peptide binding
GO:0044822 IDA poly(A) RNA binding
GO:0045069 IMP regulation of viral genome replication
GO:0045070 IMP positive regulation of viral genome replication
GO:0046790 NAS virion binding
GO:0050714 IMP positive regulation of protein secretion
GO:0050900 TAS leukocyte migration
GO:0051082 TAS unfolded protein binding
GO:0070062 IDA extracellular vesicular exosome
GO:0075713 TAS establishment of integrated proviral latency

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000055795 Gm5160 protein_coding Mus_musculus
ENSMUSG00000071866 Ppia protein_coding Mus_musculus

Loading