ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: X-ray repair complementing defective repair in Chinese hamster cells 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196419 XRCC6 9606 + 22:41621119-41664048 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000359308 XRCC6-003 41621350-41664039 protein_coding
  ENST00000360079 XRCC6-001 41621119-41664039 protein_coding
  ENST00000402580 XRCC6-002 41621295-41664048 protein_coding
  ENST00000405506 XRCC6-005 41621983-41664034 protein_coding
  ENST00000405878 XRCC6-006 41621461-41664039 protein_coding
  ENST00000428575 XRCC6-201 41621163-41664048 protein_coding
  ENST00000464116 XRCC6-007 41621285-41628318 retained_intron
  ENST00000478914 XRCC6-008 41656953-41661699 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000359308ENST00000360079ENST00000402580ENST00000405506ENST00000405878ENST00000464116
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000359308 N/A N/A N/A N/A 1.251±0.73
ENST00000360079 N/A 38.077±20.93 N/A N/A 57.252±38.14
ENST00000402580 51.041±17.05 65.592±17.45 13.365±0.00 37.703±0.00 15.897±15.46
ENST00000405506 137.127±0.29 17.542±0.15 19.715±0.00 N/A 30.535±19.60
ENST00000405878 N/A 57.907±18.59 N/A 83.655±0.00 45.883±34.50
ENST00000464116 N/A 185.302±1.95 N/A N/A 628.363±128.77

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000V7 CIL_0000V7_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000723 IEA:TAS telomere maintenance
GO:0000783 TAS nuclear telomere cap complex
GO:0003677 NAS:IEA DNA binding
GO:0003684 IEA damaged DNA binding
GO:0003690 TAS double-stranded DNA binding
GO:0003691 IDA double-stranded telomeric DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006266 TAS DNA ligation
GO:0006281 TAS DNA repair
GO:0006302 TAS double-strand break repair
GO:0006303 TAS:IEA double-strand break repair via nonhomologous end joining
GO:0006351 IEA transcription, DNA-templated
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007420 IEA brain development
GO:0008022 IPI protein C-terminus binding
GO:0010212 IEA response to ionizing radiation
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0032481 TAS positive regulation of type I interferon production
GO:0032508 IEA DNA duplex unwinding
GO:0033151 IEA V(D)J recombination
GO:0042162 IEA telomeric DNA binding
GO:0043234 IEA protein complex
GO:0043564 IEA:IDA Ku70:Ku80 complex
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0050769 IEA positive regulation of neurogenesis
GO:0051575 IMP 5'-deoxyribose-5-phosphate lyase activity
GO:0070419 IDA nonhomologous end joining complex
GO:0071475 IEA cellular hyperosmotic salinity response
GO:0071481 IEA cellular response to X-ray
GO:0075713 TAS establishment of integrated proviral latency

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071551 xrcc6 protein_coding Danio_rerio
ENSMUSG00000022471 Xrcc6 protein_coding Mus_musculus

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