ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: major histocompatibility complex, class II, DQ alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196735 HLA-DQA1 9606 + 6:32628179-32647062 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343139 HLA-DQA1-001 32637357-32643652 protein_coding
  ENST00000374949 HLA-DQA1-009 32637420-32643017 protein_coding
  ENST00000395363 HLA-DQA1-004 32637401-32643652 protein_coding
  ENST00000422863 HLA-DQA1-010 32628179-32637531 protein_coding
  ENST00000460633 HLA-DQA1-003 32637431-32647062 retained_intron
  ENST00000482745 HLA-DQA1-002 32637427-32643272 nonsense_mediated_decay
  ENST00000496318 HLA-DQA1-007 32637406-32642981 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHUVECENST00000343139ENST00000422863ENST00000460633ENST00000496318
Transcript ID HAoEC HHSEC HUVEC
ENST00000343139 0.013±0.00 5.375±0.00 N/A
ENST00000422863 0.168±0.08 N/A 0.153±0.00
ENST00000460633 0.019±0.01 0.474±0.00 0.013±0.00
ENST00000496318 0.040±0.00 N/A 0.062±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002XS CIL_0002XS_0008 CGP
CIL_0001PL CIL_0001PL_0006 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005764 IEA lysosome
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006955 NAS:IEA immune response
GO:0009897 IEA external side of plasma membrane
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032395 TAS MHC class II receptor activity
GO:0032588 TAS trans-Golgi network membrane
GO:0034341 IEA response to interferon-gamma
GO:0042605 ISS peptide antigen binding
GO:0042613 ISS:IEA MHC class II protein complex
GO:0045582 IEA positive regulation of T cell differentiation
GO:0048002 IEA antigen processing and presentation of peptide antigen
GO:0050852 TAS T cell receptor signaling pathway
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031745 si:zfos-2070c2.4 protein_coding Danio_rerio
ENSDARG00000070206 si:zfos-2070c2.1 protein_coding Danio_rerio
ENSDARG00000074816 si:zfos-367g9.1 protein_coding Danio_rerio
ENSDARG00000075932 si:ch73-211l2.3 protein_coding Danio_rerio
ENSDARG00000086294 CU914776.1 protein_coding Danio_rerio
ENSMUSG00000036594 H2-Aa protein_coding Mus_musculus

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