ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: SLIT-ROBO Rho GTPase activating protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196935 SRGAP1 9606 + 12:63844293-64162221 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355086 SRGAP1-001 63844293-64162221 protein_coding
  ENST00000537556 SRGAP1-002 63844803-64081924 retained_intron
  ENST00000537585 SRGAP1-006 64111811-64116005 retained_intron
  ENST00000542381 SRGAP1-005 64042794-64043627 retained_intron
  ENST00000542841 SRGAP1-004 64127637-64142566 retained_intron
  ENST00000543397 SRGAP1-003 63982525-64143780 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000355086ENST00000542841ENST00000543397
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000355086 0.380±0.00 0.457±0.20 0.216±0.00 0.636±0.00 0.597±0.34
ENST00000542841 N/A N/A N/A N/A 1.563±0.00
ENST00000543397 N/A 0.919±0.23 N/A 0.918±0.00 0.992±0.48

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002KR CIL_0002KR_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005100 IEA Rho GTPase activator activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007266 IEA Rho protein signal transduction
GO:0007411 TAS axon guidance
GO:0016477 IEA cell migration
GO:0017048 IEA Rho GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0051056 TAS regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007461 srgap1 protein_coding Danio_rerio
ENSDARG00000045789 srgap2b protein_coding Danio_rerio
ENSMUSG00000020121 Srgap1 protein_coding Mus_musculus

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