ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ATP-binding cassette, sub-family B (MDR/TAP), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197150 ABCB8 9606 + 7:151028422-151047782 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000297504 ABCB8-003 151028450-151045562 protein_coding
  ENST00000358849 ABCB8-005 151028423-151047782 protein_coding
  ENST00000461373 ABCB8-012 151028423-151033842 protein_coding
  ENST00000462605 ABCB8-016 151028450-151033242 retained_intron
  ENST00000466514 ABCB8-007 151028450-151045562 nonsense_mediated_decay
  ENST00000466956 ABCB8-017 151028450-151034599 processed_transcript
  ENST00000469410 ABCB8-021 151028657-151033060 processed_transcript
  ENST00000470645 ABCB8-004 151028450-151042030 nonsense_mediated_decay
  ENST00000471796 ABCB8-015 151028450-151033034 processed_transcript
  ENST00000472698 ABCB8-018 151028473-151031626 processed_transcript
  ENST00000477092 ABCB8-010 151028467-151037570 protein_coding
  ENST00000477719 ABCB8-009 151028464-151037524 protein_coding
  ENST00000482309 ABCB8-006 151028426-151045409 nonsense_mediated_decay
  ENST00000482899 ABCB8-011 151037688-151045562 retained_intron
  ENST00000488370 ABCB8-019 151028476-151033698 processed_transcript
  ENST00000488551 ABCB8-020 151028476-151034547 nonsense_mediated_decay
  ENST00000488826 ABCB8-013 151028437-151033750 processed_transcript
  ENST00000489192 ABCB8-014 151028438-151034551 nonsense_mediated_decay
  ENST00000491920 ABCB8-023 151035619-151037586 protein_coding
  ENST00000493338 ABCB8-022 151032930-151034597 processed_transcript
  ENST00000498578 ABCB8-008 151028462-151045563 protein_coding
  ENST00000542328 ABCB8-201 151028422-151047782 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000297504ENST00000358849ENST00000466514ENST00000477092ENST00000477719ENST00000482309ENST00000482899ENST00000498578ENST00000542328
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000297504 7.016±0.00 2.850±0.41 N/A N/A 5.552±3.80
ENST00000358849 2.432±0.00 1.657±0.71 N/A 1.006±0.00 2.100±0.67
ENST00000466514 26.015±9.30 3.968±0.00 4.212±0.00 4.720±0.00 3.303±0.00
ENST00000477092 N/A 5.542±2.12 N/A 4.562±0.00 6.258±3.31
ENST00000477719 N/A N/A N/A N/A 1.251±0.83
ENST00000482309 N/A 4.181±1.25 N/A N/A 3.871±1.23
ENST00000482899 N/A N/A N/A N/A 1.419±1.01
ENST00000498578 N/A 3.584±1.16 N/A 1.989±0.00 5.412±3.00
ENST00000542328 N/A N/A N/A N/A 0.630±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008T1 CIL_0008T1_0001 VISTA
CIL_0004O6 CIL_0004O6_0001 CGP
CIL_0004O7 CIL_0004O7_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 TAS transporter activity
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005739 IDA mitochondrion
GO:0005740 TAS mitochondrial envelope
GO:0005743 IEA mitochondrial inner membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 TAS:IEA transport
GO:0016020 TAS membrane
GO:0016021 IBA:IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0042626 IBA:IEA ATPase activity, coupled to transmembrane movement of substances
GO:0043190 TAS ATP-binding cassette (ABC) transporter complex
GO:0055085 IBA:IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056672 abcb8 protein_coding Danio_rerio
ENSMUSG00000028973 Abcb8 protein_coding Mus_musculus

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