ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: KN motif and ankyrin repeat domains 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197256 KANK2 9606 - 19:11164267-11197791 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000586659 KANK2-001 11164267-11197521 protein_coding
  ENST00000587317 KANK2-013 11166309-11170415 processed_transcript
  ENST00000588724 KANK2-007 11193946-11197548 protein_coding
  ENST00000588787 KANK2-005 11164270-11175947 protein_coding
  ENST00000589359 KANK2-003 11166558-11197547 protein_coding
  ENST00000589427 KANK2-014 11196058-11197183 retained_intron
  ENST00000589894 KANK2-015 11169676-11194511 protein_coding
  ENST00000590095 KANK2-009 11195623-11196227 processed_transcript
  ENST00000590400 KANK2-006 11192432-11197791 retained_intron
  ENST00000590685 KANK2-012 11193637-11195192 protein_coding
  ENST00000592215 KANK2-010 11194553-11196229 processed_transcript
  ENST00000592675 KANK2-008 11192881-11195685 protein_coding
  ENST00000592903 KANK2-011 11194504-11197530 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000586659ENST00000587317ENST00000588724ENST00000588787ENST00000589359ENST00000589894ENST00000592903
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000586659 5.955±2.43 3.318±0.00 4.105±0.00 5.742±5.51
ENST00000587317 N/A N/A N/A 3.680±2.80
ENST00000588724 N/A N/A N/A 17.847±0.00
ENST00000588787 5.287±2.15 N/A 4.717±0.00 6.295±4.56
ENST00000589359 2.425±1.38 N/A N/A 1.293±1.02
ENST00000589894 N/A N/A N/A 0.640±0.31
ENST00000592903 N/A N/A N/A 12.872±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000167 CIL_000167_0001 CGP
CIL_0001EZ CIL_0001EZ_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0008285 IDA negative regulation of cell proliferation
GO:0033147 IDA negative regulation of intracellular estrogen receptor signaling pathway
GO:0043069 IDA negative regulation of programmed cell death
GO:2000134 IDA negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018393 kank2 protein_coding Danio_rerio
ENSMUSG00000032194 Kank2 protein_coding Mus_musculus

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