ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: dishevelled-binding antagonist of beta-catenin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197380 DACT3 9606 - 19:46647612-46661138 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300875 DACT3-002 46647612-46654657 protein_coding
  ENST00000391916 DACT3-001 46647612-46661138 protein_coding
  ENST00000410105 DACT3-003 46650148-46661138 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000300875ENST00000391916ENST00000410105
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000300875 0.272±0.00 2.945±4.74 0.398±0.00 0.166±0.00 0.207±0.17
ENST00000391916 N/A 5.880±6.33 N/A N/A 0.314±0.26
ENST00000410105 0.060±0.00 0.067±0.02 0.245±0.00 0.039±0.00 0.096±0.07

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005080 ISS protein kinase C binding
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0010719 IEA negative regulation of epithelial to mesenchymal transition
GO:0016055 IEA Wnt signaling pathway
GO:0030178 IDA negative regulation of Wnt signaling pathway
GO:0030308 IDA negative regulation of cell growth
GO:0035414 IDA negative regulation of catenin import into nucleus
GO:0042802 IEA identical protein binding
GO:0051018 ISS protein kinase A binding
GO:0070097 ISS delta-catenin binding
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087910 dact3a protein_coding Danio_rerio
ENSMUSG00000078794 Dact3 protein_coding Mus_musculus

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