ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: occludin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197822 OCLN 9606 + 5:69492292-69558104 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355237 OCLN-001 69492292-69558104 protein_coding
  ENST00000396442 OCLN-002 69492790-69553671 protein_coding
  ENST00000510666 OCLN-004 69544744-69553711 retained_intron
  ENST00000514370 OCLN-003 69544692-69553999 processed_transcript
  ENST00000538151 OCLN-201 69504177-69558104 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000355237ENST00000396442ENST00000538151
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000355237 N/A 0.232±0.06 N/A 0.480±0.36
ENST00000396442 N/A 0.559±0.33 0.940±0.00 1.360±1.27
ENST00000538151 0.297±0.00 0.586±0.36 N/A 0.496±0.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000774 CIL_000774_0002 CGP
CIL_0005K7 CIL_0005K7_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005923 IDA:IEA tight junction
GO:0006461 TAS protein complex assembly
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008119 IEA thiopurine S-methyltransferase activity
GO:0008757 IEA S-adenosylmethionine-dependent methyltransferase activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0016327 IEA apicolateral plasma membrane
GO:0019904 IPI protein domain specific binding
GO:0030054 IDA cell junction
GO:0030139 IEA endocytic vesicle
GO:0031410 IDA cytoplasmic vesicle
GO:0032259 IEA methylation
GO:0045216 IMP cell-cell junction organization
GO:0046498 IEA S-adenosylhomocysteine metabolic process
GO:0046500 IEA S-adenosylmethionine metabolic process
GO:0070830 IMP tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003091 oclnb protein_coding Danio_rerio
ENSDARG00000005108 oclna protein_coding Danio_rerio
ENSMUSG00000021638 Ocln protein_coding Mus_musculus

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