ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: aldo-keto reductase family 1, member B10 (aldose reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198074 AKR1B10 9606 + 7:134527592-134541408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000359579 AKR1B10-001 134527592-134541408 protein_coding
  ENST00000475559 AKR1B10-005 134527620-134537087 processed_transcript
  ENST00000496435 AKR1B10-002 134537613-134541408 processed_transcript
  ENST00000498818 AKR1B10-004 134537580-134541408 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000359579ENST00000475559ENST00000496435ENST00000498818
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000359579 0.138±0.00 0.183±0.14 0.062±0.00 N/A 0.124±0.12
ENST00000475559 N/A 0.155±0.04 N/A N/A 0.056±0.03
ENST00000496435 N/A 0.474±0.23 N/A 0.289±0.00 0.133±0.06
ENST00000498818 N/A 1.073±0.00 N/A N/A 0.257±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002GX CIL_0002GX_0001 CGP
CIL_0002GY CIL_0002GY_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0001758 IDA retinal dehydrogenase activity
GO:0004033 TAS aldo-keto reductase (NADP) activity
GO:0005515 IPI protein binding
GO:0005764 IEA lysosome
GO:0005829 TAS cytosol
GO:0006081 TAS cellular aldehyde metabolic process
GO:0007586 TAS digestion
GO:0007603 TAS phototransduction, visible light
GO:0008202 TAS steroid metabolic process
GO:0016488 IDA farnesol catabolic process
GO:0044597 IMP daunorubicin metabolic process
GO:0044598 IMP doxorubicin metabolic process
GO:0045550 IDA geranylgeranyl reductase activity
GO:0047718 IDA indanol dehydrogenase activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045598 si:dkey-180p18.9 protein_coding Danio_rerio
ENSMUSG00000029762 Akr1b8 protein_coding Mus_musculus
ENSMUSG00000052131 Akr1b7 protein_coding Mus_musculus
ENSMUSG00000061758 Akr1b10 protein_coding Mus_musculus

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