ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: alcohol dehydrogenase 4 (class II), pi polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198099 ADH4 9606 - 4:99123657-99157792 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265512 ADH4-001 99123667-99144297 protein_coding
  ENST00000503416 ADH4-008 99131652-99142811 retained_intron
  ENST00000503944 ADH4-007 99136537-99143206 processed_transcript
  ENST00000504125 ADH4-006 99131674-99144268 protein_coding
  ENST00000504581 ADH4-010 99141639-99157792 processed_transcript
  ENST00000504894 ADH4-003 99139143-99144297 nonsense_mediated_decay
  ENST00000505590 ADH4-005 99124379-99144276 protein_coding
  ENST00000506705 ADH4-004 99126594-99144276 nonsense_mediated_decay
  ENST00000508393 ADH4-002 99123657-99144297 protein_coding
  ENST00000509471 ADH4-009 99124364-99136537 nonsense_mediated_decay
  ENST00000512499 ADH4-011 99131631-99144238 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHUVECENST00000265512ENST00000504125ENST00000506705ENST00000508393
Transcript ID HAoEC HHSEC HUVEC
ENST00000265512 0.067±0.03 0.593±0.00 0.073±0.01
ENST00000504125 N/A N/A 0.056±0.00
ENST00000506705 0.031±0.00 N/A N/A
ENST00000508393 N/A N/A 0.031±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005C1 CIL_0005C1_0006 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 IDA retinoid metabolic process
GO:0003960 ISS NADPH:quinone reductase activity
GO:0004022 IDA alcohol dehydrogenase (NAD) activity
GO:0004024 IDA alcohol dehydrogenase activity, zinc-dependent
GO:0004032 IEA alditol:NADP+ 1-oxidoreductase activity
GO:0004745 IDA retinol dehydrogenase activity
GO:0005503 IDA all-trans retinal binding
GO:0005829 TAS cytosol
GO:0006066 IDA alcohol metabolic process
GO:0006067 IEA ethanol metabolic process
GO:0006069 IDA ethanol oxidation
GO:0006081 IDA cellular aldehyde metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008270 IDA:IEA zinc ion binding
GO:0016491 IEA oxidoreductase activity
GO:0016620 IDA oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0016747 IEA transferase activity, transferring acyl groups other than amino-acyl groups
GO:0019115 IDA benzaldehyde dehydrogenase activity
GO:0019841 IDA retinol binding
GO:0035276 IEA ethanol binding
GO:0042572 IDA retinol metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046164 ISS alcohol catabolic process
GO:0051287 IDA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:1901661 ISS quinone metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024278 adh8b protein_coding Danio_rerio
ENSDARG00000087262 zgc:63568 protein_coding Danio_rerio
ENSDARG00000088366 zgc:77938 protein_coding Danio_rerio
ENSDARG00000091211 adh8a protein_coding Danio_rerio
ENSMUSG00000037797 Adh4 protein_coding Mus_musculus

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