ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: intersectin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198399 ITSN2 9606 - 2:24202864-24360714 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355123 ITSN2-001 24202864-24360714 protein_coding
  ENST00000361999 ITSN2-002 24202864-24360309 protein_coding
  ENST00000406921 ITSN2-004 24220319-24360508 protein_coding
  ENST00000407704 ITSN2-006 24311620-24360472 processed_transcript
  ENST00000412011 ITSN2-003 24286323-24360509 protein_coding
  ENST00000416160 ITSN2-008 24238933-24248699 protein_coding
  ENST00000427234 ITSN2-010 24203282-24209948 nonsense_mediated_decay
  ENST00000443927 ITSN2-012 24310344-24360490 protein_coding
  ENST00000449392 ITSN2-011 24204363-24208316 nonsense_mediated_decay
  ENST00000469848 ITSN2-007 24293261-24295711 retained_intron
  ENST00000478720 ITSN2-005 24202864-24205693 retained_intron
  ENST00000479575 ITSN2-009 24205266-24210329 retained_intron
  ENST00000622089 ITSN2-201 24202867-24328118 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000355123ENST00000361999ENST00000406921ENST00000412011ENST00000416160ENST00000443927ENST00000622089
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000355123 N/A N/A N/A N/A 3.588±1.46
ENST00000361999 0.212±0.00 1.630±0.72 N/A N/A 3.638±2.02
ENST00000406921 N/A N/A N/A N/A 1.302±0.00
ENST00000412011 N/A N/A N/A N/A 4.304±2.89
ENST00000416160 0.867±0.47 3.155±3.06 6.957±0.00 N/A 3.978±2.22
ENST00000443927 N/A N/A N/A N/A 6.132±5.76
ENST00000622089 N/A 1.689±0.59 N/A 4.063±0.00 3.111±1.90

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000024 CIL_000024_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0006897 IEA endocytosis
GO:0009967 TAS positive regulation of signal transduction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000161 itsn2a protein_coding Danio_rerio
ENSDARG00000054973 itsn2b protein_coding Danio_rerio
ENSMUSG00000020640 Itsn2 protein_coding Mus_musculus

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