ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: major histocompatibility complex, class II, DR beta 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198502 HLA-DRB5 9606 - 6:32517343-32530287 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374975 HLA-DRB5-001 32517343-32530287 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000374975
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000374975 0.434±0.36 0.084±0.05 94.936±0.00 0.132±0.09

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001PL CIL_0001PL_0007 CGP
CIL_0001PK CIL_0001PK_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0005515 IEA protein binding
GO:0005765 IDA lysosomal membrane
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0031902 IDA late endosome membrane
GO:0032588 TAS trans-Golgi network membrane
GO:0042605 ISS peptide antigen binding
GO:0042613 ISS:IEA MHC class II protein complex
GO:0050852 TAS T cell receptor signaling pathway
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041705 si:busm1-228j01.6 protein_coding Danio_rerio
ENSDARG00000056330 mhc2dbb protein_coding Danio_rerio
ENSDARG00000074510 si:busm1-104n07.3 protein_coding Danio_rerio
ENSDARG00000076307 si:zfos-2070c2.3 protein_coding Danio_rerio
ENSDARG00000079105 mhc2dab protein_coding Danio_rerio
ENSDARG00000088872 si:busm1-228j01.4 protein_coding Danio_rerio
ENSMUSG00000060586 H2-Eb1 protein_coding Mus_musculus
ENSMUSG00000067341 H2-Eb2 protein_coding Mus_musculus

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