ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: SRY (sex determining region Y)-box 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000203883 SOX18 9606 - 20:64047582-64049641 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340356 SOX18-001 64047582-64049641 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000340356
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000340356 230.968±25.74 33.385±11.63 277.987±0.00 73.197±0.00 93.137±114.58

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004F5 CIL_0004F5_0001 CGP
CIL_0003V3 CIL_0003V3_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IEP angiogenesis
GO:0001568 IEA blood vessel development
GO:0001570 ISS vasculogenesis
GO:0001701 IEA in utero embryonic development
GO:0001942 IEA hair follicle development
GO:0001944 ISS vasculature development
GO:0001945 IEA lymph vessel development
GO:0001946 IMP lymphangiogenesis
GO:0001947 ISS heart looping
GO:0003151 ISS outflow tract morphogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007507 IEA heart development
GO:0022405 IMP hair cycle process
GO:0035050 ISS embryonic heart tube development
GO:0042789 IDA mRNA transcription from RNA polymerase II promoter
GO:0043534 IEP blood vessel endothelial cell migration
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IEA nuclear transcription factor complex
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048469 IEA cell maturation
GO:0048866 IEA stem cell fate specification
GO:0060214 ISS endocardium formation
GO:0060836 ISS lymphatic endothelial cell differentiation
GO:0060956 ISS endocardial cell differentiation
GO:0061028 IMP establishment of endothelial barrier
GO:0072091 IEA regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058598 sox18 protein_coding Danio_rerio
ENSMUSG00000046470 Sox18 protein_coding Mus_musculus

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