ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: hydroxysteroid (17-beta) dehydrogenase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204228 HSD17B8 9606 + 6:33204642-33206831 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374662 HSD17B8-001 33204642-33206831 protein_coding
  ENST00000469186 HSD17B8-002 33204686-33206449 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000374662ENST00000469186
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000374662 2.235±1.04 3.860±2.75 3.095±0.00 2.067±0.00 2.886±3.71
ENST00000469186 N/A 0.577±0.50 N/A N/A 0.605±0.52

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003857 IDA 3-hydroxyacyl-CoA dehydrogenase activity
GO:0004303 IDA estradiol 17-beta-dehydrogenase activity
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005740 IEA mitochondrial envelope
GO:0005759 IDA mitochondrial matrix
GO:0005886 IEA plasma membrane
GO:0006633 IEA fatty acid biosynthetic process
GO:0006703 IEA estrogen biosynthetic process
GO:0008152 IEA metabolic process
GO:0008209 IEA androgen metabolic process
GO:0008210 IEA estrogen metabolic process
GO:0016020 IEA membrane
GO:0016491 IEA oxidoreductase activity
GO:0047035 IEA testosterone dehydrogenase (NAD+) activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001169 hsd17b8 protein_coding Danio_rerio
ENSMUSG00000073422 H2-Ke6 protein_coding Mus_musculus

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