ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: major histocompatibility complex, class II, DO alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204252 HLA-DOA 9606 - 6:33004178-33009612 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000229829 HLA-DOA-001 33004178-33009612 protein_coding
  ENST00000374813 HLA-DOA-003 33007497-33009579 protein_coding
  ENST00000450833 HLA-DOA-201 33006746-33009560 protein_coding
  ENST00000467465 HLA-DOA-002 33008061-33009582 processed_transcript
  ENST00000485901 HLA-DOA-004 33006801-33008054 retained_intron
  ENST00000490305 HLA-DOA-005 33006607-33007384 processed_transcript
  ENST00000495532 HLA-DOA-006 33007445-33008124 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000229829ENST00000450833
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000229829 0.134±0.13 0.630±0.00 0.039±0.00 0.033±0.03
ENST00000450833 0.191±0.00 N/A N/A 0.044±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001PI CIL_0001PI_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002587 IDA negative regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IDA MHC class II protein complex binding
GO:0032395 TAS MHC class II receptor activity
GO:0042613 IDA:IEA MHC class II protein complex
GO:0045580 IEA regulation of T cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031745 si:zfos-2070c2.4 protein_coding Danio_rerio
ENSDARG00000070206 si:zfos-2070c2.1 protein_coding Danio_rerio
ENSDARG00000074816 si:zfos-367g9.1 protein_coding Danio_rerio
ENSDARG00000075932 si:ch73-211l2.3 protein_coding Danio_rerio
ENSDARG00000086294 CU914776.1 protein_coding Danio_rerio
ENSMUSG00000024334 H2-Oa protein_coding Mus_musculus

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