ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: euchromatic histone-lysine N-methyltransferase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204371 EHMT2 9606 - 6:31879759-31897687 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375528 EHMT2-009 31879759-31897222 protein_coding
  ENST00000375530 EHMT2-007 31879759-31897677 protein_coding
  ENST00000375537 EHMT2-001 31879759-31897684 protein_coding
  ENST00000395728 EHMT2-008 31879759-31897202 protein_coding
  ENST00000436026 EHMT2-012 31883819-31887064 protein_coding
  ENST00000461880 EHMT2-006 31879759-31885141 retained_intron
  ENST00000463484 EHMT2-010 31892418-31893186 retained_intron
  ENST00000465429 EHMT2-002 31895401-31897687 retained_intron
  ENST00000477678 EHMT2-011 31884673-31887119 retained_intron
  ENST00000478491 EHMT2-005 31879759-31884806 processed_transcript
  ENST00000480912 EHMT2-003 31879759-31896504 processed_transcript
  ENST00000494816 EHMT2-004 31879759-31886437 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000375528ENST00000375530ENST00000375537ENST00000395728ENST00000461880ENST00000478491ENST00000480912ENST00000494816
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000375528 N/A 1.849±0.97 N/A N/A 3.449±1.62
ENST00000375530 N/A 3.483±1.79 N/A N/A 3.107±1.78
ENST00000375537 4.439±0.00 10.145±4.50 N/A 7.086±0.00 8.396±6.69
ENST00000395728 N/A N/A N/A N/A 2.701±2.28
ENST00000461880 N/A N/A N/A N/A 0.225±0.00
ENST00000478491 44.936±4.95 10.448±4.61 47.831±0.00 N/A 10.379±6.12
ENST00000480912 2.885±0.00 N/A N/A N/A 1.986±1.33
ENST00000494816 N/A N/A N/A N/A 0.299±0.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001PN CIL_0001PN_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0002039 IPI p53 binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005694 IEA chromosome
GO:0006275 IEA regulation of DNA replication
GO:0006306 IEA DNA methylation
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007130 IEA synaptonemal complex assembly
GO:0007281 IEA germ cell development
GO:0007286 IEA spermatid development
GO:0008270 IEA zinc ion binding
GO:0009566 IEA fertilization
GO:0010424 IEA DNA methylation on cytosine within a CG sequence
GO:0016279 IDA protein-lysine N-methyltransferase activity
GO:0016571 IEA histone methylation
GO:0018024 IEA histone-lysine N-methyltransferase activity
GO:0018027 IDA peptidyl-lysine dimethylation
GO:0034968 IEA histone lysine methylation
GO:0035265 IEA organ growth
GO:0046974 IEA histone methyltransferase activity (H3-K9 specific)
GO:0046976 IEA histone methyltransferase activity (H3-K27 specific)
GO:0051567 IEA histone H3-K9 methylation
GO:0070734 IEA histone H3-K27 methylation
GO:0070742 IEA C2H2 zinc finger domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000013787 Ehmt2 protein_coding Mus_musculus

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