ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sialidase 1 (lysosomal sialidase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204386 NEU1 9606 - 6:31857659-31862906 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375631 NEU1-001 31859052-31862906 protein_coding
  ENST00000480384 NEU1-004 31859052-31862805 retained_intron
  ENST00000491768 NEU1-002 31859052-31862822 nonsense_mediated_decay
  ENST00000495807 NEU1-005 31857659-31862796 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000375631ENST00000491768ENST00000495807
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000375631 21.594±6.38 60.558±45.15 11.306±0.00 29.898±0.00 36.463±21.72
ENST00000491768 19.049±0.97 10.188±8.88 18.299±0.00 N/A 5.973±0.13
ENST00000495807 N/A N/A N/A N/A 0.828±0.75

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004308 IDA exo-alpha-sialidase activity
GO:0005515 IEA protein binding
GO:0005764 IDA lysosome
GO:0005886 IEA plasma membrane
GO:0006665 TAS sphingolipid metabolic process
GO:0006687 TAS glycosphingolipid metabolic process
GO:0008152 IEA metabolic process
GO:0009313 IMP oligosaccharide catabolic process
GO:0016042 IEA lipid catabolic process
GO:0030054 IDA cell junction
GO:0031410 IEA cytoplasmic vesicle
GO:0043202 TAS lysosomal lumen
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0052794 IEA exo-alpha-(2->3)-sialidase activity
GO:0052795 IEA exo-alpha-(2->6)-sialidase activity
GO:0052796 IEA exo-alpha-(2->8)-sialidase activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008832 neu1 protein_coding Danio_rerio
ENSMUSG00000007038 Neu1 protein_coding Mus_musculus

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