ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: major histocompatibility complex, class I, G
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204632 HLA-G 9606 + 6:29826967-29831125 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360323 HLA-G-001 29827821-29831125 protein_coding
  ENST00000376815 HLA-G-006 29827845-29831125 protein_coding
  ENST00000376818 HLA-G-004 29827845-29831125 protein_coding
  ENST00000376828 HLA-G-002 29826967-29831125 protein_coding
  ENST00000428701 HLA-G-201 29826979-29831122 protein_coding
  ENST00000478355 HLA-G-003 29827845-29831125 retained_intron
  ENST00000478519 HLA-G-005 29827845-29831125 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000360323ENST00000376818ENST00000478519
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000360323 N/A 0.566±0.08 N/A N/A N/A
ENST00000376818 N/A 0.010±0.00 N/A N/A 0.087±0.09
ENST00000478519 52.430±4.99 4.904±1.22 7.667±0.00 18.193±0.00 6.786±6.58

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000420 CIL_000420_0003 CGP
CIL_000420 CIL_000420_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002666 IMP positive regulation of T cell tolerance induction
GO:0002767 IDA immune response-inhibiting cell surface receptor signaling pathway
GO:0005102 IPI receptor binding
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0006968 TAS cellular defense response
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0031901 TAS early endosome membrane
GO:0032735 IDA positive regulation of interleukin-12 production
GO:0042130 IDA negative regulation of T cell proliferation
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 IEA peptide antigen binding
GO:0042612 IEA MHC class I protein complex
GO:0042803 NAS protein homodimerization activity
GO:0045591 IMP positive regulation of regulatory T cell differentiation
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane
GO:2001199 IDA negative regulation of dendritic cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037334 H2-M1 protein_coding Mus_musculus
ENSMUSG00000037537 H2-M11 protein_coding Mus_musculus
ENSMUSG00000067201 H2-M9 protein_coding Mus_musculus

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