ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: tripartite motif containing 27
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204713 TRIM27 9606 - 6:28903002-28923989 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377194 TRIM27-002 28903002-28923988 protein_coding
  ENST00000377199 TRIM27-001 28903002-28923989 protein_coding
  ENST00000414543 TRIM27-003 28903002-28908989 protein_coding
  ENST00000467742 TRIM27-006 28904474-28907584 processed_transcript
  ENST00000481474 TRIM27-004 28903002-28923913 retained_intron
  ENST00000496091 TRIM27-005 28914776-28920183 processed_transcript
  ENST00000498117 TRIM27-007 28911307-28921976 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000377194ENST00000377199ENST00000414543ENST00000481474
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000377194 3.823±0.00 N/A 8.565±0.00 N/A 2.847±0.41
ENST00000377199 7.224±5.32 21.126±6.20 N/A 32.677±0.00 21.693±9.49
ENST00000414543 17.128±0.37 8.074±0.74 38.153±0.00 N/A 7.710±1.77
ENST00000481474 N/A 1.848±0.16 N/A N/A 1.682±0.74

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0002820 IMP negative regulation of adaptive immune response
GO:0003676 TAS nucleic acid binding
GO:0003677 IEA DNA binding
GO:0004714 TAS transmembrane receptor protein tyrosine kinase activity
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005768 IDA endosome
GO:0005887 TAS integral component of plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006469 IDA negative regulation of protein kinase activity
GO:0007283 TAS spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0008283 TAS cell proliferation
GO:0016020 TAS membrane
GO:0016874 IEA ligase activity
GO:0018108 TAS peptidyl-tyrosine phosphorylation
GO:0030904 IDA retromer complex
GO:0031965 IDA nuclear membrane
GO:0032720 IMP negative regulation of tumor necrosis factor production
GO:0032897 IDA negative regulation of viral transcription
GO:0034314 IDA Arp2/3 complex-mediated actin nucleation
GO:0042147 IDA retrograde transport, endosome to Golgi
GO:0045087 IDA innate immune response
GO:0045814 IDA negative regulation of gene expression, epigenetic
GO:0046872 TAS:IEA metal ion binding
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070206 IDA protein trimerization
GO:0070534 IMP protein K63-linked ubiquitination
GO:0072643 IMP interferon-gamma secretion
GO:0090281 IMP negative regulation of calcium ion import
GO:1900041 IMP negative regulation of interleukin-2 secretion
GO:1902187 IEA negative regulation of viral release from host cell

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000021326 Trim27 protein_coding Mus_musculus

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