ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: major histocompatibility complex, class I, A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000206503 HLA-A 9606 + 6:29941260-29945884 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376802 HLA-A-003 29942549-29945884 protein_coding
  ENST00000376806 HLA-A-002 29942245-29945884 protein_coding
  ENST00000376809 HLA-A-201 29942470-29945884 protein_coding
  ENST00000396634 HLA-A-001 29941260-29945884 protein_coding
  ENST00000461903 HLA-A-007 29942554-29945281 retained_intron
  ENST00000479320 HLA-A-006 29942554-29945281 retained_intron
  ENST00000495183 HLA-A-005 29942552-29945884 retained_intron
  ENST00000496081 HLA-A-004 29942548-29945884 retained_intron
  ENST00000620168 HLA-A-202 29942470-29945884 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000376802ENST00000376809ENST00000496081ENST00000620168
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000376802 N/A 38.152±4.47 N/A N/A N/A
ENST00000376809 N/A 26.305±0.00 N/A N/A 96.912±91.33
ENST00000496081 N/A N/A N/A N/A 8.205±5.34
ENST00000620168 495.771±135.21 92.048±26.13 138.825±0.00 301.951±0.00 77.050±66.59

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000420 CIL_000420_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 IEA antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0005515 IEA protein binding
GO:0005783 ISS endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006955 IEA immune response
GO:0009986 IDA:ISS cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0030881 ISS beta-2-microglobulin binding
GO:0031901 TAS early endosome membrane
GO:0042270 IDA protection from natural killer cell mediated cytotoxicity
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 IEA peptide antigen binding
GO:0042612 IEA MHC class I protein complex
GO:0046977 IDA TAP binding
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037334 H2-M1 protein_coding Mus_musculus
ENSMUSG00000037537 H2-M11 protein_coding Mus_musculus
ENSMUSG00000067201 H2-M9 protein_coding Mus_musculus

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