ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sphingosine-1-phosphate receptor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213694 S1PR3 9606 + 9:88991447-89005010 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358157 S1PR3-002 88991447-89005010 protein_coding
  ENST00000375846 S1PR3-001 88996506-89005010 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000358157ENST00000375846
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000358157 3.776±1.43 5.849±0.62 0.141±0.00 12.139±0.00 6.804±5.88
ENST00000375846 0.182±0.00 N/A 0.050±0.00 N/A 0.274±0.06

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000077 CIL_000077_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IEA cytokine production
GO:0003376 IEA sphingosine-1-phosphate signaling pathway
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0005178 IPI integrin binding
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006954 IEA inflammatory response
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007204 TAS positive regulation of cytosolic calcium ion concentration
GO:0008284 TAS positive regulation of cell proliferation
GO:0008289 TAS lipid binding
GO:0009653 TAS anatomical structure morphogenesis
GO:0016021 IEA integral component of membrane
GO:0032651 IEA regulation of interleukin-1 beta production
GO:0038036 IEA sphingosine-1-phosphate receptor activity
GO:1903141 IMP negative regulation of establishment of endothelial barrier

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000067586 S1pr3 protein_coding Mus_musculus

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