ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: general transcription factor IIH, polypeptide 4, 52kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213780 GTF2H4 9606 + 6:30908184-30914106 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259895 GTF2H4-001 30908184-30914106 protein_coding
  ENST00000376316 GTF2H4-002 30908221-30914106 protein_coding
  ENST00000453897 GTF2H4-003 30908223-30910634 protein_coding
  ENST00000475845 GTF2H4-005 30912223-30914106 retained_intron
  ENST00000483318 GTF2H4-006 30911951-30914106 retained_intron
  ENST00000487746 GTF2H4-004 30909442-30912393 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000259895ENST00000376316ENST00000453897ENST00000475845
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000259895 14.279±0.00 15.443±5.99 22.211±0.00 15.471±10.66
ENST00000376316 N/A 8.735±1.45 N/A 7.082±0.01
ENST00000453897 N/A N/A N/A 15.062±4.39
ENST00000475845 47.156±4.86 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00090O CIL_00090O_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000439 IEA core TFIIH complex
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0004672 IDA protein kinase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005675 IDA holo TFIIH complex
GO:0006200 IDA ATP catabolic process
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS:IEA nucleotide-excision repair
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006360 TAS transcription from RNA polymerase I promoter
GO:0006361 TAS transcription initiation from RNA polymerase I promoter
GO:0006362 TAS transcription elongation from RNA polymerase I promoter
GO:0006363 TAS termination of RNA polymerase I transcription
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0006468 IDA protein phosphorylation
GO:0008094 IDA DNA-dependent ATPase activity
GO:0008353 IDA RNA polymerase II carboxy-terminal domain kinase activity
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0032508 IEA DNA duplex unwinding
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036071 gtf2h4 protein_coding Danio_rerio
ENSMUSG00000001524 Gtf2h4 protein_coding Mus_musculus

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