ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin A-52 residue ribosomal protein fusion product 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000221983 UBA52 9606 + 19:18571730-18577550 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000430157 UBA52-002 18571802-18575241 protein_coding
  ENST00000442744 UBA52-001 18571860-18577550 protein_coding
  ENST00000594527 UBA52-013 18573376-18575241 protein_coding
  ENST00000595158 UBA52-009 18571882-18575234 protein_coding
  ENST00000595683 UBA52-004 18571875-18575242 protein_coding
  ENST00000596272 UBA52-012 18573355-18575241 protein_coding
  ENST00000596273 UBA52-003 18571855-18575229 protein_coding
  ENST00000596304 UBA52-005 18571730-18575202 protein_coding
  ENST00000597451 UBA52-011 18573265-18575241 protein_coding
  ENST00000598780 UBA52-008 18571927-18575170 protein_coding
  ENST00000598814 UBA52-007 18571858-18573790 retained_intron
  ENST00000599256 UBA52-006 18571879-18573748 protein_coding
  ENST00000599551 UBA52-010 18572740-18575241 protein_coding
  ENST00000599595 UBA52-014 18573285-18577290 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000430157ENST00000442744ENST00000597451
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000430157 2116.860±409.61 1000.853±400.81 185.801±0.00 585.378±0.00 1113.087±909.78
ENST00000442744 N/A 5.062±0.00 N/A N/A 46.373±51.53
ENST00000597451 2635.865±486.42 454.120±160.76 270.335±0.00 398.694±0.00 480.090±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000184 TAS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000187 TAS activation of MAPK activity
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003735 IEA structural constituent of ribosome
GO:0005515 IPI:IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0005765 IDA lysosomal membrane
GO:0005829 TAS cytosol
GO:0005840 IEA ribosome
GO:0005886 TAS plasma membrane
GO:0005975 TAS carbohydrate metabolic process
GO:0005978 TAS glycogen biosynthetic process
GO:0006006 TAS glucose metabolic process
GO:0006281 TAS DNA repair
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006412 NAS:IEA translation
GO:0006413 TAS translational initiation
GO:0006414 TAS translational elongation
GO:0006415 TAS translational termination
GO:0006464 TAS cellular protein modification process
GO:0006614 TAS SRP-dependent cotranslational protein targeting to membrane
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0007220 TAS Notch receptor processing
GO:0007249 TAS I-kappaB kinase/NF-kappaB signaling
GO:0007254 TAS JNK cascade
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010008 TAS endosome membrane
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016197 TAS endosomal transport
GO:0019058 TAS viral life cycle
GO:0019068 TAS virion assembly
GO:0019082 TAS viral protein processing
GO:0019083 TAS viral transcription
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0022625 IDA cytosolic large ribosomal subunit
GO:0030512 TAS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030666 TAS endocytic vesicle membrane
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032479 TAS regulation of type I interferon production
GO:0032480 TAS negative regulation of type I interferon production
GO:0032481 TAS positive regulation of type I interferon production
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0034220 TAS ion transmembrane transport
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043065 TAS positive regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043123 TAS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044267 TAS cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0045944 TAS positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050852 TAS T cell receptor signaling pathway
GO:0051092 TAS positive regulation of NF-kappaB transcription factor activity
GO:0051403 TAS stress-activated MAPK cascade
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0055085 TAS transmembrane transport
GO:0061024 TAS membrane organization
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070062 IDA extracellular vesicular exosome
GO:0070423 TAS nucleotide-binding oligomerization domain containing signaling pathway
GO:0071456 TAS cellular response to hypoxia
GO:0075733 TAS intracellular transport of virus
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041435 uba52 protein_coding Danio_rerio
ENSMUSG00000062742 Gm5239 protein_coding Mus_musculus
ENSMUSG00000091460 Gm7808 protein_coding Mus_musculus

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