ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: major histocompatibility complex, class II, DP beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000223865 HLA-DPB1 9606 + 6:33075926-33087201 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000416804 HLA-DPB1-002 33080672-33087201 protein_coding
  ENST00000418931 HLA-DPB1-001 33075926-33087201 protein_coding
  ENST00000428835 HLA-DPB1-008 33080487-33085889 protein_coding
  ENST00000469120 HLA-DPB1-004 33076010-33081232 retained_intron
  ENST00000471184 HLA-DPB1-006 33080386-33084012 processed_transcript
  ENST00000478189 HLA-DPB1-009 33080941-33083890 processed_transcript
  ENST00000488575 HLA-DPB1-005 33080386-33084957 processed_transcript
  ENST00000498038 HLA-DPB1-007 33080443-33085231 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000418931ENST00000428835ENST00000488575ENST00000498038
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000418931 N/A 1.700±0.80 40.598±0.00 1.931±1.75
ENST00000428835 4.681±0.53 3.468±0.70 N/A 3.386±2.07
ENST00000488575 N/A 10.526±0.00 N/A 3.699±2.77
ENST00000498038 N/A N/A N/A 0.862±0.45

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001PI CIL_0001PI_0002 CGP
CIL_0001PL CIL_0001PL_0008 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005768 IEA endosome
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0009986 IMP cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032588 TAS trans-Golgi network membrane
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042605 IDA peptide antigen binding
GO:0042613 IEA MHC class II protein complex
GO:0050852 TAS T cell receptor signaling pathway
GO:0050870 IMP positive regulation of T cell activation
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041705 si:busm1-228j01.6 protein_coding Danio_rerio
ENSDARG00000056330 mhc2dbb protein_coding Danio_rerio
ENSDARG00000074510 si:busm1-104n07.3 protein_coding Danio_rerio
ENSDARG00000076307 si:zfos-2070c2.3 protein_coding Danio_rerio
ENSDARG00000079105 mhc2dab protein_coding Danio_rerio
ENSDARG00000088872 si:busm1-228j01.4 protein_coding Danio_rerio

Loading