ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: excision repair cross-complementation group 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000225830 ERCC6 9606 - 10:49455368-49539538 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355832 ERCC6-001 49455368-49539026 protein_coding
  ENST00000462247 ERCC6-005 49530724-49539538 protein_coding
  ENST00000465653 ERCC6-002 49460024-49470281 processed_transcript
  ENST00000475116 ERCC6-003 49483368-49505999 processed_transcript
  ENST00000479652 ERCC6-004 49524936-49530737 processed_transcript
  ENST00000623073 ERCC6-009 49456655-49506480 nonsense_mediated_decay
  ENST00000623115 ERCC6-006 49458788-49502122 protein_coding
  ENST00000623318 ERCC6-007 49483386-49502157 protein_coding
  ENST00000623788 ERCC6-008 49500660-49506408 retained_intron
  ENST00000624341 ERCC6-010 49455368-49476258 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000355832ENST00000462247ENST00000623073ENST00000623115ENST00000624341
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000355832 N/A 2.884±1.83 N/A 1.163±0.00 2.843±2.13
ENST00000462247 N/A N/A N/A N/A 11.282±0.00
ENST00000623073 N/A 1.756±0.07 N/A N/A 1.243±0.67
ENST00000623115 1.301±0.00 3.301±1.52 N/A 1.013±0.00 2.440±1.11
ENST00000624341 2.063±0.42 N/A 0.554±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008ZL CIL_0008ZL_0001 VISTA
CIL_00084A CIL_00084A_0001 VISTA
CIL_0007OS CIL_0007OS_0002 UCNEbase

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000303 IEA response to superoxide
GO:0003677 IDA:IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006200 IDA ATP catabolic process
GO:0006281 TAS DNA repair
GO:0006283 IMP transcription-coupled nucleotide-excision repair
GO:0006284 IMP base-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006290 IEA pyrimidine dimer repair
GO:0006362 IEA transcription elongation from RNA polymerase I promoter
GO:0006366 NAS transcription from RNA polymerase II promoter
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0006979 IDA response to oxidative stress
GO:0007256 IEA activation of JNKK activity
GO:0007257 IEA activation of JUN kinase activity
GO:0008022 IPI protein C-terminus binding
GO:0008023 IDA transcription elongation factor complex
GO:0008094 IDA DNA-dependent ATPase activity
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009411 IDA response to UV
GO:0009636 IEA response to toxic substance
GO:0010165 IEA response to X-ray
GO:0010224 IEA response to UV-B
GO:0010332 IEA response to gamma radiation
GO:0030296 IDA protein tyrosine kinase activator activity
GO:0032403 IDA protein complex binding
GO:0032784 IDA regulation of DNA-templated transcription, elongation
GO:0032786 IDA positive regulation of DNA-templated transcription, elongation
GO:0035264 IEA multicellular organism growth
GO:0045494 IEA photoreceptor cell maintenance
GO:0047485 IPI protein N-terminus binding
GO:0061098 IDA positive regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075612 ercc6 protein_coding Danio_rerio
ENSMUSG00000054051 Ercc6 protein_coding Mus_musculus

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