ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: major histocompatibility complex, class II, DQ beta 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000232629 HLA-DQB2 9606 - 6:32756098-32763534 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000411527 HLA-DQB2-002 32756098-32763490 protein_coding
  ENST00000427449 HLA-DQB2-004 32756388-32763466 protein_coding
  ENST00000435145 HLA-DQB2-001 32756098-32763532 protein_coding
  ENST00000437316 HLA-DQB2-003 32756098-32763534 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHUVECENST00000427449ENST00000435145ENST00000437316
Transcript ID HAoEC HHSEC HUVEC
ENST00000427449 0.060±0.05 0.037±0.00 0.143±0.09
ENST00000435145 0.027±0.01 0.070±0.00 0.049±0.04
ENST00000437316 0.060±0.04 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001PL CIL_0001PL_0009 CGP
CIL_0001PK CIL_0001PK_0003 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005765 TAS lysosomal membrane
GO:0005886 TAS plasma membrane
GO:0006955 NAS:IEA immune response
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030658 TAS transport vesicle membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031295 TAS T cell costimulation
GO:0032395 NAS MHC class II receptor activity
GO:0032588 TAS trans-Golgi network membrane
GO:0042613 NAS:IEA MHC class II protein complex
GO:0050852 TAS T cell receptor signaling pathway
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041705 si:busm1-228j01.6 protein_coding Danio_rerio
ENSDARG00000056330 mhc2dbb protein_coding Danio_rerio
ENSDARG00000074510 si:busm1-104n07.3 protein_coding Danio_rerio
ENSDARG00000076307 si:zfos-2070c2.3 protein_coding Danio_rerio
ENSDARG00000079105 mhc2dab protein_coding Danio_rerio
ENSDARG00000088872 si:busm1-228j01.4 protein_coding Danio_rerio
ENSMUSG00000073421 H2-Ab1 protein_coding Mus_musculus

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