ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: major histocompatibility complex, class I, B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000234745 HLA-B 9606 - 6:31353872-31357188 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000412585 HLA-B-001 31353872-31357187 protein_coding
  ENST00000434333 HLA-B-003 31355507-31357188 protein_coding
  ENST00000463574 HLA-B-005 31355122-31355802 retained_intron
  ENST00000474381 HLA-B-009 31355522-31356905 retained_intron
  ENST00000481849 HLA-B-008 31353872-31354806 retained_intron
  ENST00000497377 HLA-B-007 31353872-31355076 retained_intron
  ENST00000498007 HLA-B-002 31355391-31357179 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000412585ENST00000481849ENST00000497377
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000412585 837.907±49.87 75.311±27.72 315.190±0.00 450.075±0.00 68.026±71.29
ENST00000481849 N/A 75.968±4.64 540.875±0.00 N/A 114.703±35.44
ENST00000497377 N/A N/A N/A N/A 0.640±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000420 CIL_000420_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002474 IEA:TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002667 IMP regulation of T cell anergy
GO:0005102 IPI receptor binding
GO:0005515 IEA protein binding
GO:0005783 ISS:IDA endoplasmic reticulum
GO:0005794 ISS:IDA Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006955 IEA:NAS immune response
GO:0009986 ISS cell surface
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019882 IEA antigen processing and presentation
GO:0030670 TAS phagocytic vesicle membrane
GO:0031901 TAS early endosome membrane
GO:0032655 IMP regulation of interleukin-12 production
GO:0032675 IMP regulation of interleukin-6 production
GO:0042270 IDA protection from natural killer cell mediated cytotoxicity
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 ISS peptide antigen binding
GO:0042612 ISS:IEA MHC class I protein complex
GO:0050776 TAS regulation of immune response
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071556 TAS integral component of lumenal side of endoplasmic reticulum membrane
GO:2001198 IMP regulation of dendritic cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037334 H2-M1 protein_coding Mus_musculus
ENSMUSG00000037537 H2-M11 protein_coding Mus_musculus
ENSMUSG00000067201 H2-M9 protein_coding Mus_musculus

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