ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Rho GTPase activating protein 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000241484 ARHGAP8 9606 + 22:44752558-44862788 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336963 ARHGAP8-003 44752603-44862788 protein_coding
  ENST00000356099 ARHGAP8-004 44752606-44862784 protein_coding
  ENST00000389772 ARHGAP8-005 44786457-44862784 nonsense_mediated_decay
  ENST00000389774 ARHGAP8-001 44752558-44862784 protein_coding
  ENST00000396119 ARHGAP8-012 44752586-44809098 protein_coding
  ENST00000412433 ARHGAP8-010 44752705-44814718 protein_coding
  ENST00000447333 ARHGAP8-013 44752586-44825591 nonsense_mediated_decay
  ENST00000460809 ARHGAP8-002 44752574-44850963 retained_intron
  ENST00000469342 ARHGAP8-016 44859661-44862463 retained_intron
  ENST00000469872 ARHGAP8-011 44765229-44786508 processed_transcript
  ENST00000495219 ARHGAP8-017 44786552-44808809 retained_intron
  ENST00000498310 ARHGAP8-014 44801820-44825551 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HUVECENST00000460809
Transcript ID HUVEC
ENST00000460809 0.138±0.07

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003JU CIL_0003JU_0001 CGP
CIL_00054G CIL_00054G_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005100 IDA Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000078954 Arhgap8 protein_coding Mus_musculus

Loading