ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: NLR family, apoptosis inhibitory protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000249437 NAIP 9606 - 5:70968483-71025114 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000194097 NAIP-201 70968483-71020910 protein_coding
  ENST00000315147 NAIP-004 70968483-70987150 retained_intron
  ENST00000447012 NAIP-008 71002930-71011772 nonsense_mediated_decay
  ENST00000503719 NAIP-202 70968483-71024373 protein_coding
  ENST00000508426 NAIP-006 70970050-71020710 protein_coding
  ENST00000508794 NAIP-003 70998121-71020774 retained_intron
  ENST00000514857 NAIP-007 70970247-70976228 protein_coding
  ENST00000517649 NAIP-001 70968483-71024687 protein_coding
  ENST00000519014 NAIP-005 71003598-71020730 nonsense_mediated_decay
  ENST00000523981 NAIP-002 70969820-71025114 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000315147ENST00000447012ENST00000503719
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000315147 N/A 0.286±0.33 4.743±0.00 0.355±0.00 0.450±0.33
ENST00000447012 0.804±0.00 0.369±0.19 N/A N/A 0.641±0.32
ENST00000503719 N/A N/A N/A N/A 0.067±0.01

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004ZC CIL_0004ZC_0001 CGP
CIL_0004ZF CIL_0004ZF_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IMP ATP binding
GO:0005737 ISS cytoplasm
GO:0006954 IEA inflammatory response
GO:0007399 TAS nervous system development
GO:0016323 ISS basolateral plasma membrane
GO:0043027 IEA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043524 TAS negative regulation of neuron apoptotic process
GO:0045087 IEA innate immune response
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000021640 Naip1 protein_coding Mus_musculus
ENSMUSG00000071203 Naip5 protein_coding Mus_musculus
ENSMUSG00000078942 Naip6 protein_coding Mus_musculus
ENSMUSG00000078945 Naip2 protein_coding Mus_musculus

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