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$value = array(
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$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

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$settings = array(
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	'isWindows' => false,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

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DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
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DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 301
GeneController::show() - APP/Controller/GeneController.php, line 301
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

• HOME
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Gene Info
Description:	gap junction protein, alpha 5, 40kDa
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSG00000265107	GJA5	9606	-	1:147756199-147773362	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENST00000430508		GJA5-002	147758484-147773354	protein_coding
	ENST00000579774		GJA5-001	147756199-147760606	protein_coding
	ENST00000621517		GJA5-201	147756200-147773362	protein_coding

Expression Patterns Split around values. Cell Line Name Tissue Condition Heat Map Numeric Values Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC ENST00000430508 N/A 1.088±0.95 N/A N/A 2.241±4.81 ENST00000579774 0.266±0.19 0.438±0.51 0.222±0.00 0.210±0.00 0.131±0.10 ENST00000621517 N/A 2.142±2.02 N/A N/A 1.073±2.01

Conserved Regions
Region ID	Sub-Region	Region Type
CIL_0000UA	CIL_0000UA_0002	CGP

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0001501	IEA	skeletal system development
GO:0001525	IEP	angiogenesis
GO:0001568	IEA	blood vessel development
GO:0003071	IEA	renal system process involved in regulation of systemic arterial blood pressure
GO:0003073	IEA	regulation of systemic arterial blood pressure
GO:0003105	IEA	negative regulation of glomerular filtration
GO:0003151	IMP	outflow tract morphogenesis
GO:0003158	IEA	endothelium development
GO:0003161	IEA	cardiac conduction system development
GO:0003174	IMP	mitral valve development
GO:0003193	IMP	pulmonary valve formation
GO:0003281	IMP	ventricular septum development
GO:0003283	IMP	atrial septum development
GO:0003284	IEA	septum primum development
GO:0003294	IEA	atrial ventricular junction remodeling
GO:0005243	IEA	gap junction channel activity
GO:0005887	IDA	integral component of plasma membrane
GO:0005921	IDA	gap junction
GO:0005922	IDA	connexon complex
GO:0006813	IEA	potassium ion transport
GO:0007507	IEA	heart development
GO:0010643	IEA	cell communication by chemical coupling
GO:0010644	IEA	cell communication by electrical coupling
GO:0010652	IEA	positive regulation of cell communication by chemical coupling
GO:0014704	IDA	intercalated disc
GO:0016264	IMP	gap junction assembly
GO:0030326	IEA	embryonic limb morphogenesis
GO:0035050	IEA	embryonic heart tube development
GO:0035922	IEA	foramen ovale closure
GO:0042312	IEA	regulation of vasodilation
GO:0042995	IEA	cell projection
GO:0045776	IEA	negative regulation of blood pressure
GO:0045907	IEA	positive regulation of vasoconstriction
GO:0045909	IEA	positive regulation of vasodilation
GO:0048844	ISS	artery morphogenesis
GO:0051259	IEA	protein oligomerization
GO:0055077	IDA	gap junction hemi-channel activity
GO:0055085	IDA	transmembrane transport
GO:0055117	IMP	regulation of cardiac muscle contraction
GO:0060307	IEA	regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060371	IMP	regulation of atrial cardiac muscle cell membrane depolarization
GO:0060373	IEA	regulation of ventricular cardiac muscle cell membrane depolarization
GO:0060412	IEA	ventricular septum morphogenesis
GO:0060413	IEA	atrial septum morphogenesis
GO:0061337	IEA	cardiac conduction
GO:0071253	IEA	connexin binding
GO:0086005	IEA	ventricular cardiac muscle cell action potential
GO:0086014	IMP	atrial cardiac muscle cell action potential
GO:0086015	IEA	SA node cell action potential
GO:0086053	IMP	AV node cell to bundle of His cell communication by electrical coupling
GO:0086064	IDA	cell communication by electrical coupling involved in cardiac conduction
GO:0086065	IEA	cell communication involved in cardiac conduction
GO:0086067	IEA	AV node cell to bundle of His cell communication
GO:0086069	IMP	bundle of His cell to Purkinje myocyte communication
GO:0086075	IMP	gap junction channel activity involved in cardiac conduction electrical coupling
GO:0086077	IDA	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
GO:0086091	IEA	regulation of heart rate by cardiac conduction
GO:1900133	IEA	regulation of renin secretion into blood stream
GO:1900825	IEA	regulation of membrane depolarization during cardiac muscle cell action potential
GO:1990029	IEA	vasomotion

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000040065	cx45.6		protein_coding	Danio_rerio
ENSDARG00000069450	cx41.8		protein_coding	Danio_rerio
ENSMUSG00000057123	Gja5		protein_coding	Mus_musculus

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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

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		'27d53785bfcd771f1901030b4bb87d02' => '`Gene`.`gene_biotype`',
		'b93574bf8a03f2d6f6486e920115e0d1' => '`Gene`.`annotation_version`',
		'1c4a3f5d90070e8ea1c62ca077df603e' => '`Gene`.`gene_description`',
		'8ca7a0c53312b8ae3cfa40a9d814adac' => '`Gene`'
	),
	'fields' => array(
		'47cba37bb7792f95f7499f6996d48351' => array(
			(int) 0 => '`Gene`.`id`',
			(int) 1 => '`Gene`.`gene_version`',
			(int) 2 => '`Gene`.`tax_id`',
			(int) 3 => '`Gene`.`assembly`',
			(int) 4 => '`Gene`.`chromosome`',
			(int) 5 => '`Gene`.`strand`',
			(int) 6 => '`Gene`.`start`',
			(int) 7 => '`Gene`.`end`',
			(int) 8 => '`Gene`.`gene_name`',
			(int) 9 => '`Gene`.`gene_source`',
			(int) 10 => '`Gene`.`gene_biotype`',
			(int) 11 => '`Gene`.`annotation_version`',
			(int) 12 => '`Gene`.`gene_description`'
		)
	)
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??