ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: lysine (K)-specific methyltransferase 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000272333 KMT2B 9606 + 19:35718019-35738878 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000420124 KMT2B-001 35718019-35738878 protein_coding
  ENST00000585476 KMT2B-004 35735220-35738878 retained_intron
  ENST00000586308 KMT2B-005 35737468-35738496 retained_intron
  ENST00000592092 KMT2B-006 35733258-35737156 retained_intron
  ENST00000606995 KMT2B-008 35720902-35721529 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000420124ENST00000585476
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000420124 3.383±0.19 4.045±1.58 7.656±0.00 3.363±0.00 5.408±3.44
ENST00000585476 10.025±0.00 N/A N/A N/A 6.419±3.39

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001541 IEA ovarian follicle development
GO:0003677 IEA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0009994 IEA oocyte differentiation
GO:0016458 IEA gene silencing
GO:0030728 IEA ovulation
GO:0034968 IEA histone lysine methylation
GO:0035097 IDA:IEA histone methyltransferase complex
GO:0042800 IDA:IEA histone methyltransferase activity (H3-K4 specific)
GO:0048096 NAS chromatin-mediated maintenance of transcription
GO:0051568 IMP:IEA histone H3-K4 methylation
GO:0051569 IEA regulation of histone H3-K4 methylation
GO:0080182 IEA histone H3-K4 trimethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060697 kmt2bb protein_coding Danio_rerio
ENSDARG00000062962 kmt2ba protein_coding Danio_rerio
ENSMUSG00000006307 Kmt2b protein_coding Mus_musculus

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