ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: cystathionine-beta-synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000274276 CBS 9606 - 21:6444869-6468040 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000398168 CBS-001 6444869-6467532 protein_coding
  ENST00000617706 CBS-201 6444873-6468040 protein_coding
  ENST00000618024 CBS-002 6444869-6468040 protein_coding
  ENST00000622914 CBS-005 6447132-6467534 processed_transcript
  ENST00000623939 CBS-007 6456880-6461713 processed_transcript
  ENST00000624406 CBS-009 6444869-6467509 protein_coding
  ENST00000624691 CBS-006 6444869-6460082 retained_intron
  ENST00000624808 CBS-003 6447261-6450632 processed_transcript
  ENST00000624921 CBS-008 6457901-6467483 processed_transcript
  ENST00000624934 CBS-004 6445433-6467532 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHUVECENST00000398168ENST00000622914ENST00000623939ENST00000624406ENST00000624691ENST00000624808ENST00000624921ENST00000624934
Transcript ID HAoEC HHSEC HUVEC
ENST00000398168 N/A N/A 0.694±0.00
ENST00000622914 0.081±0.02 N/A 0.157±0.09
ENST00000623939 0.091±0.06 N/A 0.333±0.34
ENST00000624406 N/A N/A 0.374±0.00
ENST00000624691 0.045±0.02 N/A 0.087±0.07
ENST00000624808 N/A N/A 0.068±0.01
ENST00000624921 0.078±0.03 N/A 0.099±0.05
ENST00000624934 0.115±0.00 0.037±0.00 0.322±0.38

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000MP CIL_0000MP_0002 CGP
CIL_0000MQ CIL_0000MQ_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000096 TAS sulfur amino acid metabolic process
GO:0004122 IDA:IEA cystathionine beta-synthase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006535 IEA cysteine biosynthetic process from serine
GO:0006563 IDA L-serine metabolic process
GO:0006565 IDA L-serine catabolic process
GO:0019343 IEA cysteine biosynthetic process via cystathionine
GO:0019346 TAS transsulfuration
GO:0019448 IDA L-cysteine catabolic process
GO:0019899 IPI enzyme binding
GO:0020037 IMP heme binding
GO:0030170 IDA pyridoxal phosphate binding
GO:0030554 IEA adenyl nucleotide binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043418 IDA homocysteine catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0050667 IDA homocysteine metabolic process
GO:0070814 ISS hydrogen sulfide biosynthetic process
GO:0072341 IDA modified amino acid binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010946 cbsb protein_coding Danio_rerio
ENSDARG00000053500 cbsa protein_coding Danio_rerio
ENSMUSG00000024039 Cbs protein_coding Mus_musculus

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