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ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: RAB7B, member RAS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000276600 RAB7B 9606 - 1:205976740-206003461 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000617070 RAB7B-002 205976740-206003413 protein_coding
  ENST00000617991 RAB7B-201 205976741-205994439 protein_coding
  ENST00000622969 RAB7B-004 205983743-205992580 protein_coding
  ENST00000623597 RAB7B-003 205976741-205994423 nonsense_mediated_decay
  ENST00000623893 RAB7B-001 205977699-206003461 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000617070ENST00000622969ENST00000623597ENST00000623893
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000617070 0.052±0.00 0.364±0.13 0.149±0.00 N/A 0.078±0.05
ENST00000622969 N/A N/A N/A 0.256±0.00 0.098±0.08
ENST00000623597 N/A 0.058±0.05 0.115±0.00 N/A 0.095±0.04
ENST00000623893 N/A 0.260±0.10 N/A N/A 0.044±0.03

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005764 IDA lysosome
GO:0005770 IDA late endosome
GO:0005794 IDA Golgi apparatus
GO:0005802 IDA trans-Golgi network
GO:0006184 IEA GTP catabolic process
GO:0006886 IEA intracellular protein transport
GO:0006913 IEA nucleocytoplasmic transport
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0032755 IMP positive regulation of interleukin-6 production
GO:0034144 ISS negative regulation of toll-like receptor 4 signaling pathway
GO:0034164 ISS negative regulation of toll-like receptor 9 signaling pathway
GO:0034499 IMP late endosome to Golgi transport
GO:0045335 IDA phagocytic vesicle
GO:0045654 IMP positive regulation of megakaryocyte differentiation
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026098 RAB7B protein_coding Danio_rerio
ENSMUSG00000052688 Rab7b protein_coding Mus_musculus

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