ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: acetyl-CoA carboxylase alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000278540 ACACA 9606 - 17:37084988-37406818 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000612007 ACACA-007 37328962-37365568 non_stop_decay
  ENST00000612120 ACACA-021 37207730-37225571 processed_transcript
  ENST00000612895 ACACA-002 37084994-37299767 protein_coding
  ENST00000612926 ACACA-020 37247902-37248676 retained_intron
  ENST00000613146 ACACA-011 37221518-37359121 retained_intron
  ENST00000613776 ACACA-014 37087222-37122794 retained_intron
  ENST00000614333 ACACA-017 37360205-37368727 processed_transcript
  ENST00000614428 ACACA-009 37084994-37359116 protein_coding
  ENST00000614438 ACACA-019 37328645-37330399 protein_coding
  ENST00000614450 ACACA-022 37200429-37222028 processed_transcript
  ENST00000614482 ACACA-013 37086876-37161835 nonsense_mediated_decay
  ENST00000614789 ACACA-008 37284838-37359116 protein_coding
  ENST00000615229 ACACA-010 37274217-37406672 nonsense_mediated_decay
  ENST00000616317 ACACA-001 37084988-37406780 protein_coding
  ENST00000616352 ACACA-004 37284838-37406780 protein_coding
  ENST00000617548 ACACA-005 37284838-37406780 nonsense_mediated_decay
  ENST00000617649 ACACA-003 37086817-37299767 protein_coding
  ENST00000618053 ACACA-025 37086880-37088983 protein_coding
  ENST00000618351 ACACA-015 37360233-37406818 processed_transcript
  ENST00000618575 ACACA-024 37161600-37188294 retained_intron
  ENST00000619245 ACACA-023 37188303-37193458 retained_intron
  ENST00000619546 ACACA-012 37084998-37205812 protein_coding
  ENST00000621960 ACACA-018 37277988-37359096 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000613146ENST00000614428ENST00000616317ENST00000617649ENST00000619546
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000613146 4.899±1.04 N/A 13.549±4.36
ENST00000614428 6.374±2.62 6.716±0.00 8.316±4.32
ENST00000616317 1.836±0.30 N/A 1.627±0.43
ENST00000617649 3.400±0.61 N/A 4.104±0.00
ENST00000619546 3.719±1.44 3.243±0.00 4.863±1.80

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00085Q CIL_00085Q_0001 VISTA
CIL_00085M CIL_00085M_0001 VISTA
CIL_0008DP CIL_0008DP_0001 VISTA
CIL_0008GS CIL_0008GS_0001 VISTA
CIL_0005HT CIL_0005HT_0002 CGP
CIL_0007ND CIL_0007ND_0067 UCNEbase
CIL_0005SZ CIL_0005SZ_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001894 IEA tissue homeostasis
GO:0003824 IEA catalytic activity
GO:0003989 ISS:IEA acetyl-CoA carboxylase activity
GO:0004075 IEA biotin carboxylase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0005829 ISS cytosol
GO:0006084 ISS acetyl-CoA metabolic process
GO:0006112 TAS energy reserve metabolic process
GO:0006629 IEA lipid metabolic process
GO:0006633 ISS:IEA fatty acid biosynthetic process
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0006768 TAS biotin metabolic process
GO:0006853 TAS carnitine shuttle
GO:0008152 IEA metabolic process
GO:0008716 IEA D-alanine-D-alanine ligase activity
GO:0016874 IEA ligase activity
GO:0019432 TAS triglyceride biosynthetic process
GO:0031325 TAS positive regulation of cellular metabolic process
GO:0035338 TAS long-chain fatty-acyl-CoA biosynthetic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044268 IEA multicellular organismal protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0051289 ISS protein homotetramerization
GO:0055088 IEA lipid homeostasis
GO:0070062 IDA extracellular vesicular exosome
GO:2001295 IEA malonyl-CoA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078512 acaca protein_coding Danio_rerio
ENSMUSG00000020532 Acaca protein_coding Mus_musculus

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