ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002028 Kmt2a 10090 - 9:44803355-44881296 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002095 Kmt2a-201 44803355-44881274 protein_coding
  ENSMUST00000114689 Kmt2a-001 44803355-44881296 protein_coding
  ENSMUST00000128768 Kmt2a-002 44841563-44881296 protein_coding
  ENSMUST00000138119 Kmt2a-004 44814680-44820115 nonsense_mediated_decay
  ENSMUST00000152241 Kmt2a-003 44822735-44848184 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000002095ENSMUST00000114689ENSMUST00000138119ENSMUST00000152241
Transcript ID C166 Tie2+ EC mES
ENSMUST00000002095 5.854±1.25 3.904±2.88 4.354±1.81
ENSMUST00000114689 1.219±0.33 N/A N/A
ENSMUST00000138119 N/A N/A 9.017±0.00
ENSMUST00000152241 N/A N/A 6.452±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00081E CIL_00081E_0002 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006306 IMP DNA methylation
GO:0006351 IEA transcription, DNA-templated
GO:0006461 IEA protein complex assembly
GO:0008270 ISS zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0009952 IGI anterior/posterior pattern specification
GO:0032411 IEA positive regulation of transporter activity
GO:0035097 ISS histone methyltransferase complex
GO:0035162 IMP embryonic hemopoiesis
GO:0042800 ISS histone methyltransferase activity (H3-K4 specific)
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043984 ISS histone H4-K16 acetylation
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045322 ISS unmethylated CpG binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0051568 ISS histone H3-K4 methylation
GO:0051569 IMP regulation of histone H3-K4 methylation
GO:0070577 ISS lysine-acetylated histone binding
GO:0071339 ISS MLL1 complex
GO:0080182 IEA histone H3-K4 trimethylation
GO:2001040 IEA positive regulation of cellular response to drug

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004537 kmt2a protein_coding Danio_rerio
ENSG00000118058 KMT2A lysine (K)-specific methyltransferase 2A protein_coding Homo_sapiens

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