ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003184 Irf3 10090 + 7:44997648-45002848 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003284 Irf3-001 44997648-45002848 protein_coding
  ENSMUST00000107834 Irf3-005 44997949-45002389 protein_coding
  ENSMUST00000107835 Irf3-002 44997666-45002389 protein_coding
  ENSMUST00000124069 Irf3-003 44997680-45002390 retained_intron
  ENSMUST00000127011 Irf3-008 45000501-45001257 processed_transcript
  ENSMUST00000130610 Irf3-004 44997689-45002401 retained_intron
  ENSMUST00000145233 Irf3-007 45000167-45001087 processed_transcript
  ENSMUST00000145728 Irf3-006 44998326-45000445 processed_transcript
  ENSMUST00000146355 Irf3-009 45001387-45002390 processed_transcript

Mus musculus Ensembl GRCm38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000003284ENSMUST00000107834ENSMUST00000107835ENSMUST00000130610ENSMUST00000146355
Transcript ID C166 Tie2+ EC mES
ENSMUST00000003284 N/A 5.462±0.71 11.346±1.24
ENSMUST00000107834 8.746±1.63 N/A N/A
ENSMUST00000107835 6.302±0.00 10.559±1.74 N/A
ENSMUST00000130610 13.145±1.96 16.904±1.17 7.849±0.39
ENSMUST00000146355 N/A N/A 23.676±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0009617 IDA response to bacterium
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032496 IDA response to lipopolysaccharide
GO:0032727 IMP positive regulation of interferon-alpha production
GO:0032728 TAS positive regulation of interferon-beta production
GO:0042802 IEA identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 IDA response to exogenous dsRNA
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045087 IEA innate immune response
GO:0045351 IGI type I interferon biosynthetic process
GO:0045358 IDA negative regulation of interferon-beta biosynthetic process
GO:0050689 IDA negative regulation of defense response to virus by host
GO:0050715 IEA positive regulation of cytokine secretion
GO:0051607 IMP defense response to virus
GO:0060340 IMP positive regulation of type I interferon-mediated signaling pathway
GO:0071359 IEA cellular response to dsRNA
GO:0097300 IMP programmed necrotic cell death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076251 irf3 protein_coding Danio_rerio
ENSG00000126456 IRF3 interferon regulatory factor 3 protein_coding Homo_sapiens

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