ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004056 Akt2 10090 + 7:27591552-27640826 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000051356 Akt2-003 27605858-27639453 protein_coding
  ENSMUST00000085917 Akt2-013 27608662-27638170 protein_coding
  ENSMUST00000108342 Akt2-005 27592458-27633266 protein_coding
  ENSMUST00000108343 Akt2-002 27605817-27639448 protein_coding
  ENSMUST00000108344 Akt2-001 27591552-27640826 protein_coding
  ENSMUST00000128540 Akt2-004 27592368-27628845 protein_coding
  ENSMUST00000136962 Akt2-009 27607748-27633246 protein_coding
  ENSMUST00000136981 Akt2-012 27636053-27637443 retained_intron
  ENSMUST00000138459 Akt2-006 27596830-27618233 protein_coding
  ENSMUST00000142365 Akt2-010 27608004-27618286 protein_coding
  ENSMUST00000143347 Akt2-011 27628525-27634811 retained_intron
  ENSMUST00000143499 Akt2-008 27605797-27628869 protein_coding
  ENSMUST00000147263 Akt2-007 27593546-27616346 processed_transcript
  ENSMUST00000167435 Akt2-201 27591746-27639450 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000051356ENSMUST00000085917ENSMUST00000108344ENSMUST00000136981ENSMUST00000167435
Transcript ID C166 Tie2+ EC mES
ENSMUST00000051356 27.324±2.69 4.797±0.00 2.467±0.00
ENSMUST00000085917 N/A 1.250±0.00 N/A
ENSMUST00000108344 N/A 1.254±0.80 5.138±1.47
ENSMUST00000136981 N/A 4.486±1.84 N/A
ENSMUST00000167435 22.218±2.33 2.273±1.25 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005886 IMP plasma membrane
GO:0005938 IMP cell cortex
GO:0005978 IEA glycogen biosynthetic process
GO:0006006 IEA glucose metabolic process
GO:0006417 IEA regulation of translation
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0008286 IDA insulin receptor signaling pathway
GO:0008643 IEA carbohydrate transport
GO:0010748 IEA negative regulation of plasma membrane long-chain fatty acid transport
GO:0010907 IEA positive regulation of glucose metabolic process
GO:0031340 IMP positive regulation of vesicle fusion
GO:0032000 IEA positive regulation of fatty acid beta-oxidation
GO:0032287 IMP peripheral nervous system myelin maintenance
GO:0032587 IMP ruffle membrane
GO:0032859 IGI activation of Ral GTPase activity
GO:0032869 IDA cellular response to insulin stimulus
GO:0045725 IEA positive regulation of glycogen biosynthetic process
GO:0046326 IEA positive regulation of glucose import
GO:0065002 IMP intracellular protein transmembrane transport
GO:0072659 IGI protein localization to plasma membrane
GO:0090314 IMP positive regulation of protein targeting to membrane
GO:2000147 IEA positive regulation of cell motility
GO:2001275 IGI positive regulation of glucose import in response to insulin stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011219 akt2 protein_coding Danio_rerio
ENSG00000105221 AKT2 v-akt murine thymoma viral oncogene homolog 2 protein_coding Homo_sapiens

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