ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005958 Ephb3 10090 + 16:21204755-21223305 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006112 Ephb3-001 21204755-21223304 protein_coding
  ENSMUST00000159575 Ephb3-003 21216817-21223305 retained_intron
  ENSMUST00000160053 Ephb3-004 21221686-21222687 retained_intron
  ENSMUST00000161063 Ephb3-002 21211095-21222967 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000006112ENSMUST00000159575ENSMUST00000161063
Transcript ID C166 Tie2+ EC mES
ENSMUST00000006112 19.832±2.32 0.049±0.01 3.088±2.12
ENSMUST00000159575 N/A 0.071±0.04 1.012±0.00
ENSMUST00000161063 N/A 0.015±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0001655 IMP urogenital system development
GO:0005003 ISS ephrin receptor activity
GO:0005005 TAS transmembrane-ephrin receptor activity
GO:0005524 IEA ATP binding
GO:0005887 ISS integral component of plasma membrane
GO:0007411 IMP axon guidance
GO:0007413 IMP axonal fasciculation
GO:0008046 IDA axon guidance receptor activity
GO:0016477 IMP cell migration
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021952 IDA central nervous system projection neuron axonogenesis
GO:0022038 IMP corpus callosum development
GO:0022407 ISS regulation of cell-cell adhesion
GO:0031290 IDA retinal ganglion cell axon guidance
GO:0032314 ISS regulation of Rac GTPase activity
GO:0034446 ISS substrate adhesion-dependent cell spreading
GO:0042995 IEA cell projection
GO:0043088 ISS regulation of Cdc42 GTPase activity
GO:0046777 ISS protein autophosphorylation
GO:0048013 ISS ephrin receptor signaling pathway
GO:0048538 IMP thymus development
GO:0048546 IMP digestive tract morphogenesis
GO:0050770 IDA regulation of axonogenesis
GO:0051965 IMP positive regulation of synapse assembly
GO:0060021 IMP palate development
GO:0060996 IMP dendritic spine development
GO:0060997 IMP dendritic spine morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031548 ephb3a protein_coding Danio_rerio
ENSG00000182580 EPHB3 EPH receptor B3 protein_coding Homo_sapiens

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