ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019194 Scn1b 10090 - 7:31116524-31126945 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000098548 Scn1b-001 31116524-31126945 protein_coding
  ENSMUST00000187469 Scn1b-003 31117706-31125420 retained_intron
  ENSMUST00000188002 Scn1b-004 31116524-31126844 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000098548ENSMUST00000187469ENSMUST00000188002
Transcript ID C166 Tie2+ EC mES
ENSMUST00000098548 5.539±1.23 1.710±1.02 10.893±4.11
ENSMUST00000187469 2.986±0.50 0.804±0.00 N/A
ENSMUST00000188002 4.013±0.61 0.736±0.32 3.793±1.41

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001VC CIL_0001VC_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0002028 IEA regulation of sodium ion transport
GO:0005248 IEA voltage-gated sodium channel activity
GO:0005515 IPI protein binding
GO:0007411 IMP axon guidance
GO:0010765 IEA positive regulation of sodium ion transport
GO:0010976 IGI positive regulation of neuron projection development
GO:0014704 IDA intercalated disc
GO:0017080 IEA sodium channel regulator activity
GO:0019227 IMP neuronal action potential propagation
GO:0019871 IMP sodium channel inhibitor activity
GO:0021966 IMP corticospinal neuron axon guidance
GO:0030315 IDA T-tubule
GO:0033268 IDA node of Ranvier
GO:0034706 IPI sodium channel complex
GO:0035725 IMP sodium ion transmembrane transport
GO:0040011 IMP locomotion
GO:0046684 IEA response to pyrethroid
GO:0051899 IEA membrane depolarization
GO:0060048 IEA cardiac muscle contraction
GO:0060307 IMP regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060371 IEA regulation of atrial cardiac muscle cell membrane depolarization
GO:0061337 IMP cardiac conduction
GO:0086002 IEA cardiac muscle cell action potential involved in contraction
GO:0086006 IMP voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086012 IMP membrane depolarization during cardiac muscle cell action potential
GO:0086047 IEA membrane depolarization during Purkinje myocyte cell action potential
GO:0086062 IEA voltage-gated sodium channel activity involved in Purkinje myocyte action potential
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:2000649 IEA regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060222 scn1ba protein_coding Danio_rerio
ENSDARG00000070170 SCN1B (2 of 3) protein_coding Danio_rerio
ENSG00000105711 SCN1B sodium channel, voltage-gated, type I, beta subunit protein_coding Homo_sapiens

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